Synthetic in vitro transcription circuits

Maximilian Weitz; Friedrich C. Simmel

doi:10.4161/trns.19734

Synthetic in vitro transcription circuits

Maximilian Weitz, Friedrich C. Simmel

Chair of Physics of Synthetic Biological Systems

Walter Schottky Institut

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

With the help of only two enzymes-an RNA polymerase and a ribonuclease-reduced versions of transcriptional regulatory circuits can be implemented in vitro. These circuits enable the emulation of naturally occurring biochemical networks, the exploration of biological circuit design principles and the biochemical implementation of powerful computational models.

Original language	English
Pages (from-to)	87-91
Number of pages	5
Journal	Transcription
Volume	3
Issue number	2
DOIs	https://doi.org/10.4161/trns.19734
State	Published - 2012

Keywords

DNA nanotechnology
Molecular computing
Synthetic biology
Transcription networks

Access to Document

10.4161/trns.19734

Cite this

@article{e21e1878701047c485e2862dce53718d,

title = "Synthetic in vitro transcription circuits",

abstract = "With the help of only two enzymes-an RNA polymerase and a ribonuclease-reduced versions of transcriptional regulatory circuits can be implemented in vitro. These circuits enable the emulation of naturally occurring biochemical networks, the exploration of biological circuit design principles and the biochemical implementation of powerful computational models.",

keywords = "DNA nanotechnology, Molecular computing, Synthetic biology, Transcription networks",

author = "Maximilian Weitz and Simmel, {Friedrich C.}",

year = "2012",

doi = "10.4161/trns.19734",

language = "English",

volume = "3",

pages = "87--91",

journal = "Transcription",

issn = "2154-1264",

publisher = "Taylor and Francis Ltd.",

number = "2",

}

TY - JOUR

T1 - Synthetic in vitro transcription circuits

AU - Weitz, Maximilian

AU - Simmel, Friedrich C.

PY - 2012

Y1 - 2012

N2 - With the help of only two enzymes-an RNA polymerase and a ribonuclease-reduced versions of transcriptional regulatory circuits can be implemented in vitro. These circuits enable the emulation of naturally occurring biochemical networks, the exploration of biological circuit design principles and the biochemical implementation of powerful computational models.

AB - With the help of only two enzymes-an RNA polymerase and a ribonuclease-reduced versions of transcriptional regulatory circuits can be implemented in vitro. These circuits enable the emulation of naturally occurring biochemical networks, the exploration of biological circuit design principles and the biochemical implementation of powerful computational models.

KW - DNA nanotechnology

KW - Molecular computing

KW - Synthetic biology

KW - Transcription networks

UR - http://www.scopus.com/inward/record.url?scp=84862730526&partnerID=8YFLogxK

U2 - 10.4161/trns.19734

DO - 10.4161/trns.19734

M3 - Review article

AN - SCOPUS:84862730526

SN - 2154-1264

VL - 3

SP - 87

EP - 91

JO - Transcription

JF - Transcription

IS - 2

ER -

Synthetic in vitro transcription circuits

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this