Synthesis of seven different homologous phytochelatins in metal-exposed Schizosaccharomyces pombe cells

E. Grill; E. L. Winnacker; M. H. Zenk

doi:10.1016/0014-5793(86)80309-X

Synthesis of seven different homologous phytochelatins in metal-exposed Schizosaccharomyces pombe cells

E. Grill, E. L. Winnacker, M. H. Zenk

University of Munich

Research output: Contribution to journal › Article › peer-review

119 Scopus citations

Abstract

The family of heavy metal-sequestering peptides with the formula (γ-Glu-Cys)_nGly; n = 2-8), the phytochelatins (PCs), are not restricted to higher plants. In Schizosaccharomyces pombe the occurrence of two of these peptides has previously been reported. Reinvestigation of the peptide pattern of the heavy metal-exposed fission yeast led to the discovery of five additional peptides, a pattern which now corresponds qualitatively exactly to the one in higher plants. From the kinetics of induction we propose that PCs are synthesized by consumption of glutathione or its biosynthetic precursor.

Original language	English
Pages (from-to)	115-120
Number of pages	6
Journal	FEBS Letters
Volume	197
Issue number	1-2
DOIs	https://doi.org/10.1016/0014-5793(86)80309-X
State	Published - 3 Mar 1986
Externally published	Yes

Keywords

Phytochelatin Heavy metal-binding peptide Induction kinetics Glutathione

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10.1016/0014-5793(86)80309-X

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title = "Synthesis of seven different homologous phytochelatins in metal-exposed Schizosaccharomyces pombe cells",

abstract = "The family of heavy metal-sequestering peptides with the formula (γ-Glu-Cys)nGly; n = 2-8), the phytochelatins (PCs), are not restricted to higher plants. In Schizosaccharomyces pombe the occurrence of two of these peptides has previously been reported. Reinvestigation of the peptide pattern of the heavy metal-exposed fission yeast led to the discovery of five additional peptides, a pattern which now corresponds qualitatively exactly to the one in higher plants. From the kinetics of induction we propose that PCs are synthesized by consumption of glutathione or its biosynthetic precursor.",

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T1 - Synthesis of seven different homologous phytochelatins in metal-exposed Schizosaccharomyces pombe cells

AU - Grill, E.

AU - Winnacker, E. L.

AU - Zenk, M. H.

PY - 1986/3/3

Y1 - 1986/3/3

N2 - The family of heavy metal-sequestering peptides with the formula (γ-Glu-Cys)nGly; n = 2-8), the phytochelatins (PCs), are not restricted to higher plants. In Schizosaccharomyces pombe the occurrence of two of these peptides has previously been reported. Reinvestigation of the peptide pattern of the heavy metal-exposed fission yeast led to the discovery of five additional peptides, a pattern which now corresponds qualitatively exactly to the one in higher plants. From the kinetics of induction we propose that PCs are synthesized by consumption of glutathione or its biosynthetic precursor.

AB - The family of heavy metal-sequestering peptides with the formula (γ-Glu-Cys)nGly; n = 2-8), the phytochelatins (PCs), are not restricted to higher plants. In Schizosaccharomyces pombe the occurrence of two of these peptides has previously been reported. Reinvestigation of the peptide pattern of the heavy metal-exposed fission yeast led to the discovery of five additional peptides, a pattern which now corresponds qualitatively exactly to the one in higher plants. From the kinetics of induction we propose that PCs are synthesized by consumption of glutathione or its biosynthetic precursor.

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JO - FEBS Letters

JF - FEBS Letters

IS - 1-2

ER -

Synthesis of seven different homologous phytochelatins in metal-exposed Schizosaccharomyces pombe cells

Abstract

Keywords

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