Synthesis of dolastatin 15 mimetic peptoids

Jörg Schmitt; Michael Bernd; Bernhard Kutscher; Horst Kessler

doi:10.1016/S0960-894X(98)00034-1

Synthesis of dolastatin 15 mimetic peptoids

Jörg Schmitt
, Michael Bernd
, Bernhard Kutscher
, Horst Kessler

TUM Emeriti of Excellence

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Eight peptoids have been synthesized as peptidomimetics of the cytostatic Dolastatin 15, a depsipeptide isolated from the Indian sea hare Dolabella auricularia. The compounds have been tested against several human cancer cell lines and did not show any cytostatic properties.

Original language	English
Pages (from-to)	385-388
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/S0960-894X(98)00034-1
State	Published - 17 Feb 1998

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/S0960-894X(98)00034-1

Cite this

@article{eb91c047bc564e039c7ffa5381ea1075,

title = "Synthesis of dolastatin 15 mimetic peptoids",

abstract = "Eight peptoids have been synthesized as peptidomimetics of the cytostatic Dolastatin 15, a depsipeptide isolated from the Indian sea hare Dolabella auricularia. The compounds have been tested against several human cancer cell lines and did not show any cytostatic properties.",

author = "J{\"o}rg Schmitt and Michael Bernd and Bernhard Kutscher and Horst Kessler",

note = "Funding Information: Acknowledgement: Financial support of the Fonds der Chemischen Industrie is greatfully acknowledged.",

year = "1998",

month = feb,

day = "17",

doi = "10.1016/S0960-894X(98)00034-1",

language = "English",

volume = "8",

pages = "385--388",

journal = "Bioorganic and Medicinal Chemistry Letters",

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T1 - Synthesis of dolastatin 15 mimetic peptoids

AU - Schmitt, Jörg

AU - Bernd, Michael

AU - Kutscher, Bernhard

AU - Kessler, Horst

N1 - Funding Information: Acknowledgement: Financial support of the Fonds der Chemischen Industrie is greatfully acknowledged.

PY - 1998/2/17

Y1 - 1998/2/17

N2 - Eight peptoids have been synthesized as peptidomimetics of the cytostatic Dolastatin 15, a depsipeptide isolated from the Indian sea hare Dolabella auricularia. The compounds have been tested against several human cancer cell lines and did not show any cytostatic properties.

AB - Eight peptoids have been synthesized as peptidomimetics of the cytostatic Dolastatin 15, a depsipeptide isolated from the Indian sea hare Dolabella auricularia. The compounds have been tested against several human cancer cell lines and did not show any cytostatic properties.

UR - https://www.scopus.com/pages/publications/0032539636

U2 - 10.1016/S0960-894X(98)00034-1

DO - 10.1016/S0960-894X(98)00034-1

M3 - Article

C2 - 9871690

AN - SCOPUS:0032539636

SN - 0960-894X

VL - 8

SP - 385

EP - 388

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 4

ER -

Synthesis of dolastatin 15 mimetic peptoids

Abstract

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