Synthesis of 3-trifluoromethylfurans from β,β- bis(trifluoromethyl) α,β-unsaturated ketones and tin(II) chloride

Klaus Burger, Brigitte Helmreich

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

A new building block strategy for the synthesis of 3-trifluoromethyl- substituted furans 9 and 10 is described from β,β-bis(trifluoromethyl) α,β-unsaturated ketones 2 via reductive fluoride elimination and 1,5-electrocyclization with elimination.

Original languageEnglish
Pages (from-to)348-349
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number4
DOIs
StatePublished - 1992

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