Synthesis and characterization of a new and radiolabeled high-affinity substrate for H⁺/peptide cotransporters

Keyphrases

• High Affinity 100%
• Cotransporter 100%
• Proline 80%
• Peptide Transporter 1 (PepT1) 30%
• Dipeptide 10%
• Glycine 10%
• PH Dependence 10%
• Functional Characterization 10%
• Low Capacity 10%
• Caco-2 Cells 10%
• Intact Cells 10%
• Xenopus Oocytes 10%
• Two-electrode Voltage Clamp 10%
• Voltage Clamp Technique 10%
• Transporter Proteins 10%
• Vmax 10%
• Michaelis Constant 10%
• Saturable 10%
• Maximal Velocity 10%
• Rational Synthesis 10%
• Cefadroxil 10%
• Gly-Sar 10%
• Extracellular pH 10%
• 5-Aminolevulinic Acid (5-ALA) 10%
• Hydrolysis Resistance 10%
• Cell Monolayer 10%
• Proline Uptake 10%
• Transporter Substrate 10%
• Peptide Chemistry 10%
• Capacity Processes 10%
• Design Rational 10%
• Nitroanilide 10%

Biochemistry, Genetics and Molecular Biology

• Cotransporter 100%
• Proline 80%
• Enzymatic Hydrolysis 10%
• Voltage Clamp 10%
• Xenopus laevis 10%
• Maximum Reaction Velocity 10%
• Michaelis Constant 10%
• Synapsin I 10%
• Dipeptide 10%
• Carrier Protein 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Cotransporter 100%
• Proline 80%
• Xenopus laevis 10%
• Carrier Protein 10%
• Dipeptide 10%
• Synapsin I 10%
• Carbon 14 10%
• Cefadroxil 10%
• Aminolevulinic Acid 10%