Abstract
pH oscillations generated by a nonequilibrium chemical reaction are used to switch a pH-sensitive DNA structure between two distinct conformations. The utilization of a chemical oscillator represents a novel method for achieving autonomous motion molecular devices. The oscillatory reaction is a variant of the Landolt reaction and produces pH variations in the range between pH 5 and in this range, a cytosing rich DNA strand can be switched between a random coil conformation and the folded i-motif structure. The coformational changes a monitored simultaneously with the pH value in fluorescence-resonance energy-transfer experiments.
| Original language | English |
|---|---|
| Pages (from-to) | 1894-1898 |
| Number of pages | 5 |
| Journal | Nano Letters |
| Volume | 5 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 2005 |
| Externally published | Yes |