Surface functionalization of amorphous silicon and silicon suboxides for biological applications

C. Dahmen; A. Janotta; D. Dimova-Malinovska; S. Marx; B. Jeschke; B. Nies; H. Kessler; M. Stutzmann

doi:10.1016/S0040-6090(02)01228-2

Surface functionalization of amorphous silicon and silicon suboxides for biological applications

C. Dahmen, A. Janotta, D. Dimova-Malinovska, S. Marx, B. Jeschke, B. Nies, H. Kessler, M. Stutzmann

TUM Emeriti of Excellence

Research output: Contribution to journal › Conference article › peer-review

26 Scopus citations

Abstract

We have studied the chemical modification and functionalization of the surface of hydrogenated amorphous silicon (a-Si:H) and silicon suboxides (a-SiO_x:H) for the purpose of selective cell adhesion. The preparation of hydrophobic/hydrophilic contrast on the amorphous surfaces has been investigated systematically as a function of the oxygen content by contact angle measurements. Successful functionalization of a-Si:H by hydrosilylation with methyl acrylate is reported and analyzed by thermal desorption studies as well as enzyme linked immunosorbent assays using RGD-peptide derivatives.

Original language	English
Pages (from-to)	201-207
Number of pages	7
Journal	Thin Solid Films
Volume	427
Issue number	1-2
DOIs	https://doi.org/10.1016/S0040-6090(02)01228-2
State	Published - 3 Mar 2003
Event	E-MRS, K - Strasbourg, France Duration: 18 Jun 2003 → 21 Jun 2003

Keywords

Amorphous silicon
Cell adhesion
Hydrosilylation
RGD peptides
Silicon suboxides
Surface functionalization

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10.1016/S0040-6090(02)01228-2

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title = "Surface functionalization of amorphous silicon and silicon suboxides for biological applications",

abstract = "We have studied the chemical modification and functionalization of the surface of hydrogenated amorphous silicon (a-Si:H) and silicon suboxides (a-SiOx:H) for the purpose of selective cell adhesion. The preparation of hydrophobic/hydrophilic contrast on the amorphous surfaces has been investigated systematically as a function of the oxygen content by contact angle measurements. Successful functionalization of a-Si:H by hydrosilylation with methyl acrylate is reported and analyzed by thermal desorption studies as well as enzyme linked immunosorbent assays using RGD-peptide derivatives.",

keywords = "Amorphous silicon, Cell adhesion, Hydrosilylation, RGD peptides, Silicon suboxides, Surface functionalization",

author = "C. Dahmen and A. Janotta and D. Dimova-Malinovska and S. Marx and B. Jeschke and B. Nies and H. Kessler and M. Stutzmann",

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doi = "10.1016/S0040-6090(02)01228-2",

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pages = "201--207",

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TY - JOUR

T1 - Surface functionalization of amorphous silicon and silicon suboxides for biological applications

AU - Dahmen, C.

AU - Janotta, A.

AU - Dimova-Malinovska, D.

AU - Marx, S.

AU - Jeschke, B.

AU - Nies, B.

AU - Kessler, H.

AU - Stutzmann, M.

PY - 2003/3/3

Y1 - 2003/3/3

N2 - We have studied the chemical modification and functionalization of the surface of hydrogenated amorphous silicon (a-Si:H) and silicon suboxides (a-SiOx:H) for the purpose of selective cell adhesion. The preparation of hydrophobic/hydrophilic contrast on the amorphous surfaces has been investigated systematically as a function of the oxygen content by contact angle measurements. Successful functionalization of a-Si:H by hydrosilylation with methyl acrylate is reported and analyzed by thermal desorption studies as well as enzyme linked immunosorbent assays using RGD-peptide derivatives.

AB - We have studied the chemical modification and functionalization of the surface of hydrogenated amorphous silicon (a-Si:H) and silicon suboxides (a-SiOx:H) for the purpose of selective cell adhesion. The preparation of hydrophobic/hydrophilic contrast on the amorphous surfaces has been investigated systematically as a function of the oxygen content by contact angle measurements. Successful functionalization of a-Si:H by hydrosilylation with methyl acrylate is reported and analyzed by thermal desorption studies as well as enzyme linked immunosorbent assays using RGD-peptide derivatives.

KW - Amorphous silicon

KW - Cell adhesion

KW - Hydrosilylation

KW - RGD peptides

KW - Silicon suboxides

KW - Surface functionalization

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U2 - 10.1016/S0040-6090(02)01228-2

DO - 10.1016/S0040-6090(02)01228-2

M3 - Conference article

AN - SCOPUS:0037416748

SN - 0040-6090

VL - 427

SP - 201

EP - 207

JO - Thin Solid Films

JF - Thin Solid Films

IS - 1-2

T2 - E-MRS, K

Y2 - 18 June 2003 through 21 June 2003

ER -

Surface functionalization of amorphous silicon and silicon suboxides for biological applications

Abstract

Keywords

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