Styrene-7,8-oxide in blood of workers exposed to styrene

M. Korn, W. Gfrörer, J. G. Filser, W. Kessler

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32 Scopus citations

Abstract

A field study was carried out on 13 workers exposed to styrene vapors at time-weighted average concentrations between 10 and 73 ppm. The reactive intermediate styrene-7,8-oxide was determined in blood samples using a direct gas chromatographic method. Styrene-7,8-oxide concentrations were in the range between 0.9 and 4.1 μg/l blood. Linear correlations were found between styrene-7,8-oxide in blood and styrene in ambient air and blood. For an exposure concentration of 20 ppm styrene (German MAK value) a steady-state level of about 1 μg styrene-7,8-oxide/l blood was calculated.

Original languageEnglish
Pages (from-to)524-527
Number of pages4
JournalArchives of Toxicology
Volume68
Issue number8
DOIs
StatePublished - Aug 1994
Externally publishedYes

Keywords

  • Blood concentration
  • Capillary gas chromatography
  • Field study
  • Man
  • Styrene
  • Styrene-7,8-oxide

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