Studies on the Biocompatibility of Poly(diethyl vinyl-phosphonate) with a New Fluorescent Marker

Christina Schwarzenböck; Sergei I. Vagin; Werner R. Heinz; Peter J. Nelson; Bernhard Rieger

doi:10.1002/marc.201800259

Studies on the Biocompatibility of Poly(diethyl vinyl-phosphonate) with a New Fluorescent Marker

Christina Schwarzenböck, Sergei I. Vagin, Werner R. Heinz, Peter J. Nelson, Bernhard Rieger

Wacker-Chair of Macromolecular Chemistry

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Utilization of group transfer polymerization for the synthesis of poly(diethyl vinylphosphonate) (PDEVP) allows its controlled end-group functionalization. Thus, a new fluorescent chromophore/PDEVP conjugate is prepared and subjected to biocompatibility tests on two different human cell lines. In contrast to the previous studies, the tagged polymer is not absorbed by cells from the solution and has nearly no impact on cell mortality rate.

Original language	English
Article number	1800259
Journal	Macromolecular Rapid Communications
Volume	39
Issue number	15
DOIs	https://doi.org/10.1002/marc.201800259
State	Published - Aug 2018

Keywords

biocompatibility
fluorescence
polyvinylphosphonates
thermoresponsive polymers
water-soluble polymers

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/marc.201800259

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title = "Studies on the Biocompatibility of Poly(diethyl vinyl-phosphonate) with a New Fluorescent Marker",

abstract = "Utilization of group transfer polymerization for the synthesis of poly(diethyl vinylphosphonate) (PDEVP) allows its controlled end-group functionalization. Thus, a new fluorescent chromophore/PDEVP conjugate is prepared and subjected to biocompatibility tests on two different human cell lines. In contrast to the previous studies, the tagged polymer is not absorbed by cells from the solution and has nearly no impact on cell mortality rate.",

keywords = "biocompatibility, fluorescence, polyvinylphosphonates, thermoresponsive polymers, water-soluble polymers",

author = "Christina Schwarzenb{\"o}ck and Vagin, {Sergei I.} and Heinz, {Werner R.} and Nelson, {Peter J.} and Bernhard Rieger",

note = "Publisher Copyright: {\textcopyright} 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim",

year = "2018",

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AU - Schwarzenböck, Christina

AU - Vagin, Sergei I.

AU - Heinz, Werner R.

AU - Nelson, Peter J.

AU - Rieger, Bernhard

PY - 2018/8

Y1 - 2018/8

N2 - Utilization of group transfer polymerization for the synthesis of poly(diethyl vinylphosphonate) (PDEVP) allows its controlled end-group functionalization. Thus, a new fluorescent chromophore/PDEVP conjugate is prepared and subjected to biocompatibility tests on two different human cell lines. In contrast to the previous studies, the tagged polymer is not absorbed by cells from the solution and has nearly no impact on cell mortality rate.

AB - Utilization of group transfer polymerization for the synthesis of poly(diethyl vinylphosphonate) (PDEVP) allows its controlled end-group functionalization. Thus, a new fluorescent chromophore/PDEVP conjugate is prepared and subjected to biocompatibility tests on two different human cell lines. In contrast to the previous studies, the tagged polymer is not absorbed by cells from the solution and has nearly no impact on cell mortality rate.

KW - biocompatibility

KW - fluorescence

KW - polyvinylphosphonates

KW - thermoresponsive polymers

KW - water-soluble polymers

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U2 - 10.1002/marc.201800259

DO - 10.1002/marc.201800259

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JO - Macromolecular Rapid Communications

JF - Macromolecular Rapid Communications

IS - 15

M1 - 1800259

ER -

Studies on the Biocompatibility of Poly(diethyl vinyl-phosphonate) with a New Fluorescent Marker

Abstract

Keywords

UN SDGs

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