Strong Electronic Effects on Enantioselectivity in Rhodium‐Catalyzed Hydroborations with Novel Pyrazole‐Containing Ferrocenyl Ligands

Anita Schnyder, Lukas Hintermann, Antonio Togni

Research output: Contribution to journalArticlepeer-review

178 Scopus citations

Abstract

The highest enantioselectivity yet for a hydroboration (98% ee) was achieved with the ferrocenyl ligand 1, R1 = R3 = Me, R2 = H, Ar = 4CF3C6H4, in the Rh‐catalyzed reaction of styrene with catecholborane. The influence of the substituents on both the pyrazolyl and phosphano fragments was studied, and the observations tentatively interpreted in terms of the varying electronic asymmetry they engender at the metal center. (Figure Presented.)

Original languageEnglish
Pages (from-to)931-933
Number of pages3
JournalAngewandte Chemie International Edition in English
Volume34
Issue number8
DOIs
StatePublished - 2 May 1995
Externally publishedYes

Keywords

  • asymmetric syntheses
  • complexes with P,N ligands
  • ferrocenyl ligands
  • hydroborations

Fingerprint

Dive into the research topics of 'Strong Electronic Effects on Enantioselectivity in Rhodium‐Catalyzed Hydroborations with Novel Pyrazole‐Containing Ferrocenyl Ligands'. Together they form a unique fingerprint.

Cite this