Stimulation of aflatoxin B'1 and T-2 toxin production by sorbic acid

M. Gareis, J. Bauer, A. Von Montgelas, B. Gedek

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34 Scopus citations

Abstract

Aspergillus flavus grown on yeast extract-sucrose medium produced higher amounts of aflatoxin B1 in the presence of 0.025% sorbic acid than without this chemical with a maximum at 17 days of incubation. Addition of 0.05 to 0.0125% sorbic acid stimulated T-2 toxin production of Fusarium acuminatum cultures grown on maize meal. The highest amounts of the mycotoxin were detected in 14-day-old cultures containing 0.025% sorbic acid. It is assumed that certain amounts of sorbic acid near the minimal inhibitory concentration reduce the activity of the tricarboxylic acid cycle; this may lead to an accumulation of acetyl coenzyme A, which is an essential intermediate in the biosynthesis of aflatoxin B1 and T-2 toxin.

Original languageEnglish
Pages (from-to)416-418
Number of pages3
JournalApplied and Environmental Microbiology
Volume47
Issue number2
DOIs
StatePublished - 1984
Externally publishedYes

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