Steroidrefraktäre Graftversus-host-Erkrankung Extrakorporale Bestrahlung von Leukozyten induziert Immuntoleranz

Translated title of the contribution: Steroid-refractory graft-versushost disease. Extracorporeal irradiation of leucocytes induces imiminotolerance

N. Schinwald, A. Rank, J. Tischer, H. J. Kolb

Research output: Contribution to journalArticlepeer-review

Abstract

A 42 year-old woman develops steroid refractory graft-versus-host disease (GVHD) after second allogeneic stem cell transplantation for acute myelogenous leukemia with severe GVHD of her skin with blisters, severe GVHD of her gut with watery and bloody diarrhea and GVHD of her liver with cholestasis. In a further attempt to control GVHD extracorporeal photochemotherapy is administered. The treatment exposures peripheral mononuclear cells to photoactivated psoralen before they subsequently are given back to the patient. This approach apparently offers selective immune tolerance.

Translated title of the contributionSteroid-refractory graft-versushost disease. Extracorporeal irradiation of leucocytes induces imiminotolerance
Original languageGerman
Pages (from-to)1270-1274
Number of pages5
JournalInternist
Volume50
Issue number11
DOIs
StatePublished - Nov 2009
Externally publishedYes

Fingerprint

Dive into the research topics of 'Steroid-refractory graft-versushost disease. Extracorporeal irradiation of leucocytes induces imiminotolerance'. Together they form a unique fingerprint.

Cite this