Stellenwert der extendierten pelvinen Lymphadenektomie beim Harnblasenkarzinom

M. Autenrieth; M. Retz; J. E. Gschwend

doi:10.1007/s00120-011-2665-9

Stellenwert der extendierten pelvinen Lymphadenektomie beim Harnblasenkarzinom

Translated title of the contribution: The significance of extended pelvic lymphadenectomy in bladder cancer

M. Autenrieth
, M. Retz
, J. E. Gschwend

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Despite radical surgery, invasive urothelial carcinoma has a high risk of systemic progression. This might be due to the presence of occult but already disseminated tumor cells in lymph nodes, blood, or bone marrow. In all retrospective series presented here, extended pelvic lymphadenectomy seems to provide a clear benefit for survival in pN0 and pN+ patients. Lymph node density and absolute number of positive lymph nodes appear to affect patient outcome and survival. However, only the randomized, prospective German LEA study will hopefully provide conclusive new data.

Translated title of the contribution	The significance of extended pelvic lymphadenectomy in bladder cancer
Original language	German
Pages (from-to)	1591-1594
Number of pages	4
Journal	Urologe - Ausgabe A
Volume	50
Issue number	12
DOIs	https://doi.org/10.1007/s00120-011-2665-9
State	Published - Dec 2011

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title = "Stellenwert der extendierten pelvinen Lymphadenektomie beim Harnblasenkarzinom",

abstract = "Despite radical surgery, invasive urothelial carcinoma has a high risk of systemic progression. This might be due to the presence of occult but already disseminated tumor cells in lymph nodes, blood, or bone marrow. In all retrospective series presented here, extended pelvic lymphadenectomy seems to provide a clear benefit for survival in pN0 and pN+ patients. Lymph node density and absolute number of positive lymph nodes appear to affect patient outcome and survival. However, only the randomized, prospective German LEA study will hopefully provide conclusive new data.",

keywords = "Bladder cancer, Lymphadenectomy, Prognosis, Radical surgery, Risk of systemic progression",

author = "M. Autenrieth and M. Retz and Gschwend, \{J. E.\}",

year = "2011",

month = dec,

doi = "10.1007/s00120-011-2665-9",

language = "Deutsch",

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journal = "Urologe - Ausgabe A",

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T1 - Stellenwert der extendierten pelvinen Lymphadenektomie beim Harnblasenkarzinom

AU - Autenrieth, M.

AU - Retz, M.

AU - Gschwend, J. E.

PY - 2011/12

Y1 - 2011/12

N2 - Despite radical surgery, invasive urothelial carcinoma has a high risk of systemic progression. This might be due to the presence of occult but already disseminated tumor cells in lymph nodes, blood, or bone marrow. In all retrospective series presented here, extended pelvic lymphadenectomy seems to provide a clear benefit for survival in pN0 and pN+ patients. Lymph node density and absolute number of positive lymph nodes appear to affect patient outcome and survival. However, only the randomized, prospective German LEA study will hopefully provide conclusive new data.

AB - Despite radical surgery, invasive urothelial carcinoma has a high risk of systemic progression. This might be due to the presence of occult but already disseminated tumor cells in lymph nodes, blood, or bone marrow. In all retrospective series presented here, extended pelvic lymphadenectomy seems to provide a clear benefit for survival in pN0 and pN+ patients. Lymph node density and absolute number of positive lymph nodes appear to affect patient outcome and survival. However, only the randomized, prospective German LEA study will hopefully provide conclusive new data.

KW - Bladder cancer

KW - Lymphadenectomy

KW - Prognosis

KW - Radical surgery

KW - Risk of systemic progression

UR - https://www.scopus.com/pages/publications/83655201342

U2 - 10.1007/s00120-011-2665-9

DO - 10.1007/s00120-011-2665-9

M3 - Artikel

C2 - 21918891

AN - SCOPUS:83655201342

SN - 0340-2592

VL - 50

SP - 1591

EP - 1594

JO - Urologe - Ausgabe A

JF - Urologe - Ausgabe A

IS - 12

ER -

Stellenwert der extendierten pelvinen Lymphadenektomie beim Harnblasenkarzinom

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