Abstract
By in vivo screening in zebrafish larvae, Wheeler et al. identify environmental agents that directly modulate transcriptional programs of astrocytes. The herbicide linuron exploits the unfolded protein response pathway to induce a pro-inflammatory program in reactive astrocytes that potentiates inflammatory tissue damage in the CNS.
Original language | English |
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Pages (from-to) | 416-418 |
Number of pages | 3 |
Journal | Cell |
Volume | 176 |
Issue number | 3 |
DOIs | |
State | Published - 24 Jan 2019 |
Externally published | Yes |