Stars Are Not in Outer Space: Astrocytes Respond to Environmental Cues

Research output: Contribution to journalShort surveypeer-review

Abstract

By in vivo screening in zebrafish larvae, Wheeler et al. identify environmental agents that directly modulate transcriptional programs of astrocytes. The herbicide linuron exploits the unfolded protein response pathway to induce a pro-inflammatory program in reactive astrocytes that potentiates inflammatory tissue damage in the CNS.

Original languageEnglish
Pages (from-to)416-418
Number of pages3
JournalCell
Volume176
Issue number3
DOIs
StatePublished - 24 Jan 2019
Externally publishedYes

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