Spindelzellige osteosklerotische Knochenläsion mit MDM2-Amplifikation

C. Mogler; M. Boxberg; C. Knebel; W. Weichert; K. Wörtler; K. Specht

doi:10.1007/s00292-017-0394-6

Spindelzellige osteosklerotische Knochenläsion mit MDM2-Amplifikation

Translated title of the contribution: Spindle-cell osteosclerotic bone lesion with MDM2 amplification

C. Mogler, M. Boxberg, C. Knebel, W. Weichert, K. Wörtler, K. Specht

Chair of Pathology

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

Abstract

This case report presents an osteosclerotic bone lesion in a 49-year-old man with MDM2 amplification. The final diagnosis shows metastasis to the bones from stomach cancer. In primary bone tumours, the MDM2 amplifications observed have been described for many other tumour entities as well, and therefore do not exclude bone metastasis from a carcinoma.

Translated title of the contribution	Spindle-cell osteosclerotic bone lesion with MDM2 amplification
Original language	German
Pages (from-to)	186-190
Number of pages	5
Journal	Pathologe
Volume	39
Issue number	2
DOIs	https://doi.org/10.1007/s00292-017-0394-6
State	Published - 1 Mar 2018

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10.1007/s00292-017-0394-6

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title = "Spindelzellige osteosklerotische Knochenl{\"a}sion mit MDM2-Amplifikation",

abstract = "This case report presents an osteosclerotic bone lesion in a 49-year-old man with MDM2 amplification. The final diagnosis shows metastasis to the bones from stomach cancer. In primary bone tumours, the MDM2 amplifications observed have been described for many other tumour entities as well, and therefore do not exclude bone metastasis from a carcinoma.",

keywords = "Bone neoplasms, Carcinoma, Gene amplification, Stomach neoplasm, Tumor biomarker",

author = "C. Mogler and M. Boxberg and C. Knebel and W. Weichert and K. W{\"o}rtler and K. Specht",

note = "Publisher Copyright: {\textcopyright} 2017, Springer Medizin Verlag GmbH, ein Teil von Springer Nature.",

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doi = "10.1007/s00292-017-0394-6",

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AU - Mogler, C.

AU - Boxberg, M.

AU - Knebel, C.

AU - Weichert, W.

AU - Wörtler, K.

AU - Specht, K.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - This case report presents an osteosclerotic bone lesion in a 49-year-old man with MDM2 amplification. The final diagnosis shows metastasis to the bones from stomach cancer. In primary bone tumours, the MDM2 amplifications observed have been described for many other tumour entities as well, and therefore do not exclude bone metastasis from a carcinoma.

AB - This case report presents an osteosclerotic bone lesion in a 49-year-old man with MDM2 amplification. The final diagnosis shows metastasis to the bones from stomach cancer. In primary bone tumours, the MDM2 amplifications observed have been described for many other tumour entities as well, and therefore do not exclude bone metastasis from a carcinoma.

KW - Bone neoplasms

KW - Carcinoma

KW - Gene amplification

KW - Stomach neoplasm

KW - Tumor biomarker

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M3 - Artikel

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SN - 0172-8113

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JO - Pathologe

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ER -

Spindelzellige osteosklerotische Knochenläsion mit MDM2-Amplifikation

Abstract

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