TY - GEN
T1 - Spatial-impulse-response-dependent back-projection using the non-stationary convolution in optoacoustic mesoscopy
AU - Lu, Tong
AU - Wang, Yihan
AU - Gao, Feng
AU - Zhao, Huijuan
AU - Ntziachristos, Vasilis
AU - Li, Jiao
N1 - Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.
PY - 2018
Y1 - 2018
N2 - Photoacoustic mesoscopy (PAMe), offering high-resolution (sub-100-μm) and high optical contrast imaging at the depth of 1-10 mm, generally obtains massive collection data using a high-frequency focused ultrasonic transducer. The spatial impulse response (SIR) of this focused transducer causes the distortion of measured signals in both duration and amplitude. Thus, the reconstruction method considering the SIR needs to be investigated in the computation-economic way for PAMe. Here, we present a modified back-projection algorithm, by introducing a SIR-dependent calibration process using a non-satationary convolution method. The proposed method is performed on numerical simulations and phantom experiments of microspheres with diameter of both 50 μm and 100 μm, and the improvement of image fidelity of this method is proved to be evident by methodology parameters. The results demonstrate that, the images reconstructed when the SIR of transducer is accounted for have higher contrast-to-noise ratio and more reasonable spatial resolution, compared to the common back-projection algorithm.
AB - Photoacoustic mesoscopy (PAMe), offering high-resolution (sub-100-μm) and high optical contrast imaging at the depth of 1-10 mm, generally obtains massive collection data using a high-frequency focused ultrasonic transducer. The spatial impulse response (SIR) of this focused transducer causes the distortion of measured signals in both duration and amplitude. Thus, the reconstruction method considering the SIR needs to be investigated in the computation-economic way for PAMe. Here, we present a modified back-projection algorithm, by introducing a SIR-dependent calibration process using a non-satationary convolution method. The proposed method is performed on numerical simulations and phantom experiments of microspheres with diameter of both 50 μm and 100 μm, and the improvement of image fidelity of this method is proved to be evident by methodology parameters. The results demonstrate that, the images reconstructed when the SIR of transducer is accounted for have higher contrast-to-noise ratio and more reasonable spatial resolution, compared to the common back-projection algorithm.
KW - Photoacoustic mesoscopy
KW - non-stationary convolution
KW - reconstruction algorithms
KW - spatial impulse response
UR - http://www.scopus.com/inward/record.url?scp=85047365144&partnerID=8YFLogxK
U2 - 10.1117/12.2290000
DO - 10.1117/12.2290000
M3 - Conference contribution
AN - SCOPUS:85047365144
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photons Plus Ultrasound
A2 - Wang, Lihong V.
A2 - Oraevsky, Alexander A.
PB - SPIE
T2 - Photons Plus Ultrasound: Imaging and Sensing 2018
Y2 - 28 January 2018 through 1 February 2018
ER -