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Sonogashira cross-couplings using biocompatible conditions in water

  • Technical University of Munich

Research output: Contribution to journalArticlepeer-review

65 Scopus citations

Abstract

The Pd-catalysed C-C bond formation between water soluble iodoarenes and terminal alkynes is promoted by cationic guanidinophosphines. New quantitative cross-couplings were obtained in aqueous solution at 35°C within minutes even in the presence of a protein.

Original languageEnglish
Pages (from-to)525-528
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number7
DOIs
StatePublished - 12 Feb 1998

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