TY - GEN
T1 - Smartphone based, portable optical biosensor utilizing surface plasmon resonance
AU - De Souza Filho, Carlos A.
AU - Lima, Antonio M.N.
AU - Neff, H.
PY - 2014
Y1 - 2014
N2 - A portable low cost biosensor suited for future medical diagnostic application is presented. The device comprises a custom designed scaffold, a disposable polymeric chip for surface plasmon resonance (SPR) sensing, and a smartphone. This commercial telecommunication device provides both, the optical illumination required for triggering of the SPR phenomenon and established by its active-matrix of organic light-emitting diodes (i.e., the smartphone display), whereas optical detection is obtained by means of its 1.9 Mpx CMOS image sensor that serves as the front camera. This concept does not require any additional optical device, except the SPR-chip itself and mechanical scaffold. The so-called angular interrogation mode has been employed for detection of the SPR feature. Employing appropriate data extraction algorithms, the sensitivity of the instrument approaches 10-5 RIU. This value compares well with existing laboratory style SPR-instruments, confirming feasibility of this technical approach.
AB - A portable low cost biosensor suited for future medical diagnostic application is presented. The device comprises a custom designed scaffold, a disposable polymeric chip for surface plasmon resonance (SPR) sensing, and a smartphone. This commercial telecommunication device provides both, the optical illumination required for triggering of the SPR phenomenon and established by its active-matrix of organic light-emitting diodes (i.e., the smartphone display), whereas optical detection is obtained by means of its 1.9 Mpx CMOS image sensor that serves as the front camera. This concept does not require any additional optical device, except the SPR-chip itself and mechanical scaffold. The so-called angular interrogation mode has been employed for detection of the SPR feature. Employing appropriate data extraction algorithms, the sensitivity of the instrument approaches 10-5 RIU. This value compares well with existing laboratory style SPR-instruments, confirming feasibility of this technical approach.
KW - portable biosensing
KW - signal processing
KW - surface plasmon resonance
UR - https://www.scopus.com/pages/publications/84905717244
U2 - 10.1109/I2MTC.2014.6860870
DO - 10.1109/I2MTC.2014.6860870
M3 - Conference contribution
AN - SCOPUS:84905717244
SN - 9781467363853
T3 - Conference Record - IEEE Instrumentation and Measurement Technology Conference
SP - 890
EP - 895
BT - 2014 IEEE International Instrumentation and Measurement Technology Conference
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2014 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Sustainable Development, I2MTC 2014
Y2 - 12 May 2014 through 15 May 2014
ER -