Sleep and periodic limb movements in corticobasal degeneration

Thomas C. Wetter; Hans Brunner; Victor Collado-Seidel; Claudia Trenkwalder; Juliane Winkelmann

doi:10.1016/S1389-9457(01)00097-1

Sleep and periodic limb movements in corticobasal degeneration

Thomas C. Wetter, Hans Brunner, Victor Collado-Seidel, Claudia Trenkwalder, Juliane Winkelmann

Max Planck Institute of Psychiatry

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Corticobasal degeneration (CBD) exhibits distinct features of akinesia, the 'alien limb' sign and cortical myoclonus. We report a 63-year old woman with a history of CBD for 18 months who was studied twice using all-night polysomnography with an interval of 13 months. Both recordings revealed frequent periodic arm and leg movements predominantly during non-REM sleep. To our knowledge this has not been described in a patient with CBD so far. Similar to a previous report we found REM sleep without atonia (RWA) in all REM episodes. However, the patient showed RWA and some non violent movements that fulfilled the diagnosis of subclinical REM sleep behavior disorder only in the second investigation. These observations may be due to the underlying degenerative process that involves not only cortical but also thalamic and brainstem structures.

Original language	English
Pages (from-to)	33-36
Number of pages	4
Journal	Sleep Medicine
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/S1389-9457(01)00097-1
State	Published - 2002
Externally published	Yes

Keywords

Corticobasal degeneration
Periodic leg movements
Periodic limb movements
Sleep
Subclinical REM sleep behavior disorder

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10.1016/S1389-9457(01)00097-1

Cite this

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title = "Sleep and periodic limb movements in corticobasal degeneration",

abstract = "Corticobasal degeneration (CBD) exhibits distinct features of akinesia, the 'alien limb' sign and cortical myoclonus. We report a 63-year old woman with a history of CBD for 18 months who was studied twice using all-night polysomnography with an interval of 13 months. Both recordings revealed frequent periodic arm and leg movements predominantly during non-REM sleep. To our knowledge this has not been described in a patient with CBD so far. Similar to a previous report we found REM sleep without atonia (RWA) in all REM episodes. However, the patient showed RWA and some non violent movements that fulfilled the diagnosis of subclinical REM sleep behavior disorder only in the second investigation. These observations may be due to the underlying degenerative process that involves not only cortical but also thalamic and brainstem structures.",

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AU - Wetter, Thomas C.

AU - Brunner, Hans

AU - Collado-Seidel, Victor

AU - Trenkwalder, Claudia

AU - Winkelmann, Juliane

PY - 2002

Y1 - 2002

N2 - Corticobasal degeneration (CBD) exhibits distinct features of akinesia, the 'alien limb' sign and cortical myoclonus. We report a 63-year old woman with a history of CBD for 18 months who was studied twice using all-night polysomnography with an interval of 13 months. Both recordings revealed frequent periodic arm and leg movements predominantly during non-REM sleep. To our knowledge this has not been described in a patient with CBD so far. Similar to a previous report we found REM sleep without atonia (RWA) in all REM episodes. However, the patient showed RWA and some non violent movements that fulfilled the diagnosis of subclinical REM sleep behavior disorder only in the second investigation. These observations may be due to the underlying degenerative process that involves not only cortical but also thalamic and brainstem structures.

AB - Corticobasal degeneration (CBD) exhibits distinct features of akinesia, the 'alien limb' sign and cortical myoclonus. We report a 63-year old woman with a history of CBD for 18 months who was studied twice using all-night polysomnography with an interval of 13 months. Both recordings revealed frequent periodic arm and leg movements predominantly during non-REM sleep. To our knowledge this has not been described in a patient with CBD so far. Similar to a previous report we found REM sleep without atonia (RWA) in all REM episodes. However, the patient showed RWA and some non violent movements that fulfilled the diagnosis of subclinical REM sleep behavior disorder only in the second investigation. These observations may be due to the underlying degenerative process that involves not only cortical but also thalamic and brainstem structures.

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Sleep and periodic limb movements in corticobasal degeneration

Abstract

Keywords

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