Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery in Recurrent Prostate Cancer

Thomas Horn, Markus Krönke, Isabel Rauscher, Bernhard Haller, Stephanie Robu, Hans Jürgen Wester, Margret Schottelius, Fijs W.B. van Leeuwen, Henk G. van der Poel, Matthias Heck, Jürgen E. Gschwend, Wolfgang Weber, Matthias Eiber, Tobias Maurer

Research output: Contribution to journalArticlepeer-review

77 Scopus citations

Abstract

Prostate-specific membrane antigen (PSMA) radioguided surgery leads to a substantial prostate-specific antigen (PSA) reduction in the vast majority of patients with recurrent prostate cancer. A low PSA value and the presence of only one lesion on preoperative imaging with PSMA-ligand positron emission tomography are prognostic factors for a better outcome.

Original languageEnglish
Pages (from-to)517-523
Number of pages7
JournalEuropean Urology
Volume76
Issue number4
DOIs
StatePublished - Oct 2019

Keywords

  • Biochemical recurrence
  • Prostate-specific antigen
  • Prostate-specific membrane antigen
  • Radioguided surgery
  • Salvage surgery

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