TY - GEN
T1 - Simultaneous imaging of absorption and scattering in dc diffuse optical tomography
AU - Harrach, B.
PY - 2009
Y1 - 2009
N2 - We present new results on the fundamental nonuniqueness issue in dc diffuse optical tomography (DOT) that resolve a long-standing conflict between theory and practice. Theoretically, scattering and absorption properties of the imaged media were proven to produce equivalent and thus indistinguishable effects. However, successful simultaneous reconstructions of both parameters were obtained in phantom experiments. We reconcile theory and practice by showing that the equivalence of scattering and absorption is only true for spatially smoothly varying scattering properties. Jumps in the scattering properties are however distinguishable from absorption effects. In fact, in composite tissue consisting of regions with constant scattering properties, dc intensity measurements in DOT are sufficient to simultaneously image both the absorption and the scattering coefficient. We give an intuitive justification for this result and conjecture a complete theoretical characterization of what can be reconstructed from dc intensity measurements in DOT. Essentially, the reconstructable quantities consist of the effective absorption properties together with the jumps of the scattering coefficient and its first derivative.
AB - We present new results on the fundamental nonuniqueness issue in dc diffuse optical tomography (DOT) that resolve a long-standing conflict between theory and practice. Theoretically, scattering and absorption properties of the imaged media were proven to produce equivalent and thus indistinguishable effects. However, successful simultaneous reconstructions of both parameters were obtained in phantom experiments. We reconcile theory and practice by showing that the equivalence of scattering and absorption is only true for spatially smoothly varying scattering properties. Jumps in the scattering properties are however distinguishable from absorption effects. In fact, in composite tissue consisting of regions with constant scattering properties, dc intensity measurements in DOT are sufficient to simultaneously image both the absorption and the scattering coefficient. We give an intuitive justification for this result and conjecture a complete theoretical characterization of what can be reconstructed from dc intensity measurements in DOT. Essentially, the reconstructable quantities consist of the effective absorption properties together with the jumps of the scattering coefficient and its first derivative.
KW - Diffuse optical tomography (DOT)
KW - Inter-parameter crosstalk
KW - Unique simultaneous recovery of scattering and absorption
KW - dc intensity measurements
UR - http://www.scopus.com/inward/record.url?scp=77950873672&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-03879-2_217
DO - 10.1007/978-3-642-03879-2_217
M3 - Conference contribution
AN - SCOPUS:77950873672
SN - 9783642038785
T3 - IFMBE Proceedings
SP - 776
EP - 779
BT - World Congress on Medical Physics and Biomedical Engineering
PB - Springer Verlag
T2 - World Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging
Y2 - 7 September 2009 through 12 September 2009
ER -