Shape instability of a biomembrane driven by a local softening of the underlying actin cortex

A. Boulbitch, R. Simson, D. A. Simson, R. Merkel, W. Häckl, M. Bärmann, E. Sackmann

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

A theory is presented showing that local instabilities of composite biological membranes, consisting of a lipid bilayer and an underlying actin cortex, can be triggered by a local softening of the membrane associated cytoskeleton. A function describing the local softening was introduced and a basic equation that has to be solved to determine the local shape instability arising from local softening.

Original languageEnglish
Pages (from-to)3974-3985
Number of pages12
JournalPhysical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
Volume62
Issue number3 B
DOIs
StatePublished - Sep 2000

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