S‐Glycosylated Cyclic Peptides

Manfred Gerz; Hans Matter; Horst Kessler

doi:10.1002/anie.199302691

S‐Glycosylated Cyclic Peptides

Manfred Gerz, Hans Matter, Horst Kessler

TUM Emeriti of Excellence

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of interest for the development of site‐specific drugs.

Original language	English
Pages (from-to)	269-271
Number of pages	3
Journal	Angewandte Chemie International Edition in English
Volume	32
Issue number	2
DOIs	https://doi.org/10.1002/anie.199302691
State	Published - Feb 1993

Access to Document

10.1002/anie.199302691

Cite this

@article{c435697156a64ee8afd02e5f1499ceb0,

title = "S‐Glycosylated Cyclic Peptides",

abstract = "The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of interest for the development of site‐specific drugs.",

author = "Manfred Gerz and Hans Matter and Horst Kessler",

year = "1993",

month = feb,

doi = "10.1002/anie.199302691",

language = "English",

volume = "32",

pages = "269--271",

journal = "Angewandte Chemie International Edition in English",

issn = "0570-0833",

publisher = "John Wiley and Sons Ltd",

number = "2",

}

TY - JOUR

T1 - S‐Glycosylated Cyclic Peptides

AU - Gerz, Manfred

AU - Matter, Hans

AU - Kessler, Horst

PY - 1993/2

Y1 - 1993/2

N2 - The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of interest for the development of site‐specific drugs.

AB - The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of interest for the development of site‐specific drugs.

UR - https://www.scopus.com/pages/publications/33748219729

U2 - 10.1002/anie.199302691

DO - 10.1002/anie.199302691

M3 - Article

AN - SCOPUS:33748219729

SN - 0570-0833

VL - 32

SP - 269

EP - 271

JO - Angewandte Chemie International Edition in English

JF - Angewandte Chemie International Edition in English

IS - 2

ER -

S‐Glycosylated Cyclic Peptides

Abstract

Access to Document

Other files and links

Fingerprint

Cite this