Sequential three-component and heck reactions for the synthesis of phenanthridones

Axel Jacobi Von Wangelin, Helfried Neumann, Dirk Gördes, Sandra Hübner, Christian Wendler, Stefan Klaus, Dirk Strübing, Anke Spannenberg, Haijun Jiao, Larbi El Firdoussi, Kerstin Thurow, Norbert Stoll, Matthias Beller

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


A condensation-cycloaddition-cross-coupling reaction sequence has been applied to the synthesis of phenanthridone derivatives. This novel two-step procedure is based on a three-component reaction to give 2-halobenzamide- substituted cyclohexenes, which undergo palladium-catalyzed intramolecular Heck cyclizations.

Original languageEnglish
Pages (from-to)2029-2038
Number of pages10
Issue number12
StatePublished - 1 Aug 2005
Externally publishedYes


  • Domino reactions
  • Heck reactions
  • Heterocycles palladium
  • Isomerizations


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