Sequential three-component and heck reactions for the synthesis of phenanthridones

Axel Jacobi Von Wangelin, Helfried Neumann, Dirk Gördes, Sandra Hübner, Christian Wendler, Stefan Klaus, Dirk Strübing, Anke Spannenberg, Haijun Jiao, Larbi El Firdoussi, Kerstin Thurow, Norbert Stoll, Matthias Beller

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A condensation-cycloaddition-cross-coupling reaction sequence has been applied to the synthesis of phenanthridone derivatives. This novel two-step procedure is based on a three-component reaction to give 2-halobenzamide- substituted cyclohexenes, which undergo palladium-catalyzed intramolecular Heck cyclizations.

Original languageEnglish
Pages (from-to)2029-2038
Number of pages10
JournalSynthesis
Issue number12
DOIs
StatePublished - 1 Aug 2005
Externally publishedYes

Keywords

  • Domino reactions
  • Heck reactions
  • Heterocycles palladium
  • Isomerizations

Fingerprint

Dive into the research topics of 'Sequential three-component and heck reactions for the synthesis of phenanthridones'. Together they form a unique fingerprint.

Cite this