Selective ruthenium-catalyzed transfer hydrogenations of nitriles to amines with 2-butanol

Svenja Werkmeister, Christoph Bornschein, Kathrin Junge, Matthias Beller

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Transfer your hydrogen: Fast and general transfer hydrogenation of nitriles to form primary amines is possible with a homogeneous Ru/1,4- bis(diphenylphosphino)butane (DPPB) catalyst (see scheme). The use of 2-butanol as the hydrogen-transfer reagent is essential for the selective reduction of aromatic, heteroaromatic, and aliphatic nitriles with this system.

Original languageEnglish
Pages (from-to)4437-4440
Number of pages4
JournalChemistry - A European Journal
Volume19
Issue number14
DOIs
StatePublished - 2 Apr 2013
Externally publishedYes

Keywords

  • amines
  • nitriles
  • phosphane ligands
  • ruthenium
  • transfer hydrogenation

Fingerprint

Dive into the research topics of 'Selective ruthenium-catalyzed transfer hydrogenations of nitriles to amines with 2-butanol'. Together they form a unique fingerprint.

Cite this