Selective ruthenium-catalyzed alkylation of indoles by using amines

Sebastian Imm, Sebastian Bähn, Annegret Tillack, Kathleen Mevius, Lorenz Neubert, Matthias Beller

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

(Chemical Equation Presented) Lend me your hydrogen! The first transition-metal-catalyzed alkylations of indoles with aliphatic amines proceeding under transfer hydrogenation conditions are developed (see scheme). This reaction is based on the borrowing hydrogen methodology.

Original languageEnglish
Pages (from-to)2705-2709
Number of pages5
JournalChemistry - A European Journal
Volume16
Issue number9
DOIs
StatePublished - 1 Mar 2010
Externally publishedYes

Keywords

  • Alkylation
  • Amines
  • Catalysis
  • Hydrogen transfer
  • Indoles

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