Selection of organic solvents for in situ extraction of ethanol from fermentations with Clostridium thermohydrosulfuricum

Christopher Job; Eckhart Blass; Cosima Schertler; Walter L. Staudenbauer

doi:10.1002/bbpc.19890930915

Selection of organic solvents for in situ extraction of ethanol from fermentations with Clostridium thermohydrosulfuricum

Christopher Job, Eckhart Blass, Cosima Schertler, Walter L. Staudenbauer

Technical University of Munich

Research output: Contribution to journal › Conference article › peer-review

6 Scopus citations

Abstract

Fifteen organic solvents were examined to determine their biocompatibility for in situ extraction of fermentation products from cultures of the thermophilic anaerobe Clostridium thermohydrosulfuricum. Five solvents (hexadecane, isooctane, kerosene, oleyl alcohol, Shellsol TD) were found to be non-toxic to Clostridium thermohydrosulfuricum. Interfacial tensions, phase separation and partition coefficients for ethanol of the biocompatible solvents were compared. With the exception of kerosene, these solvents showed good separation from the aqueous phase. Oleyl alcohol was found to have the highest partition coefficient for ethanol (K_D = 0.34 at 65°C). A continuous fermentation for 1200 hours showed no inhibition effects due to oleyl alcohol as extraction solvent.

Original language	English
Pages (from-to)	997-1000
Number of pages	4
Journal	Berichte der Bunsengesellschaft/Physical Chemistry Chemical Physics
Volume	93
Issue number	9
DOIs	https://doi.org/10.1002/bbpc.19890930915
State	Published - 1989
Event	Physico-Chemical Separation Processes in Biotechnology - Duration: 13 Mar 1989 → 15 Mar 1989

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title = "Selection of organic solvents for in situ extraction of ethanol from fermentations with Clostridium thermohydrosulfuricum",

abstract = "Fifteen organic solvents were examined to determine their biocompatibility for in situ extraction of fermentation products from cultures of the thermophilic anaerobe Clostridium thermohydrosulfuricum. Five solvents (hexadecane, isooctane, kerosene, oleyl alcohol, Shellsol TD) were found to be non-toxic to Clostridium thermohydrosulfuricum. Interfacial tensions, phase separation and partition coefficients for ethanol of the biocompatible solvents were compared. With the exception of kerosene, these solvents showed good separation from the aqueous phase. Oleyl alcohol was found to have the highest partition coefficient for ethanol (KD = 0.34 at 65°C). A continuous fermentation for 1200 hours showed no inhibition effects due to oleyl alcohol as extraction solvent.",

author = "Christopher Job and Eckhart Blass and Cosima Schertler and Staudenbauer, {Walter L.}",

year = "1989",

doi = "10.1002/bbpc.19890930915",

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journal = "Berichte der Bunsengesellschaft/Physical Chemistry Chemical Physics",

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number = "9",

note = "Physico-Chemical Separation Processes in Biotechnology ; Conference date: 13-03-1989 Through 15-03-1989",

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Selection of organic solvents for in situ extraction of ethanol from fermentations with Clostridium thermohydrosulfuricum. / Job, Christopher; Blass, Eckhart; Schertler, Cosima et al.
In: Berichte der Bunsengesellschaft/Physical Chemistry Chemical Physics, Vol. 93, No. 9, 1989, p. 997-1000.

Research output: Contribution to journal › Conference article › peer-review

TY - JOUR

T1 - Selection of organic solvents for in situ extraction of ethanol from fermentations with Clostridium thermohydrosulfuricum

AU - Job, Christopher

AU - Blass, Eckhart

AU - Schertler, Cosima

AU - Staudenbauer, Walter L.

PY - 1989

Y1 - 1989

N2 - Fifteen organic solvents were examined to determine their biocompatibility for in situ extraction of fermentation products from cultures of the thermophilic anaerobe Clostridium thermohydrosulfuricum. Five solvents (hexadecane, isooctane, kerosene, oleyl alcohol, Shellsol TD) were found to be non-toxic to Clostridium thermohydrosulfuricum. Interfacial tensions, phase separation and partition coefficients for ethanol of the biocompatible solvents were compared. With the exception of kerosene, these solvents showed good separation from the aqueous phase. Oleyl alcohol was found to have the highest partition coefficient for ethanol (KD = 0.34 at 65°C). A continuous fermentation for 1200 hours showed no inhibition effects due to oleyl alcohol as extraction solvent.

AB - Fifteen organic solvents were examined to determine their biocompatibility for in situ extraction of fermentation products from cultures of the thermophilic anaerobe Clostridium thermohydrosulfuricum. Five solvents (hexadecane, isooctane, kerosene, oleyl alcohol, Shellsol TD) were found to be non-toxic to Clostridium thermohydrosulfuricum. Interfacial tensions, phase separation and partition coefficients for ethanol of the biocompatible solvents were compared. With the exception of kerosene, these solvents showed good separation from the aqueous phase. Oleyl alcohol was found to have the highest partition coefficient for ethanol (KD = 0.34 at 65°C). A continuous fermentation for 1200 hours showed no inhibition effects due to oleyl alcohol as extraction solvent.

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U2 - 10.1002/bbpc.19890930915

DO - 10.1002/bbpc.19890930915

M3 - Conference article

AN - SCOPUS:0024737603

SN - 0005-9021

VL - 93

SP - 997

EP - 1000

JO - Berichte der Bunsengesellschaft/Physical Chemistry Chemical Physics

JF - Berichte der Bunsengesellschaft/Physical Chemistry Chemical Physics

IS - 9

T2 - Physico-Chemical Separation Processes in Biotechnology

Y2 - 13 March 1989 through 15 March 1989

ER -

Selection of organic solvents for in situ extraction of ethanol from fermentations with Clostridium thermohydrosulfuricum

Abstract

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