Scanning tunneling microscopy of lipid films and embedded biomolecules

J. K.H. Hörber; C. A. Lang; T. W. Hänsch; W. M. Heckl; H. Möhwald

doi:10.1016/0009-2614(88)80169-6

Scanning tunneling microscopy of lipid films and embedded biomolecules

J. K.H. Hörber
, C. A. Lang
, T. W. Hänsch
, W. M. Heckl
, H. Möhwald

Chair of Science communication and technology assessment

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

We have observed the ordered molecular structure of fatty acid and phospholipid Langmuir-Blodgett films with a scanning tunneling microscope. Besides confirming earlier studies of cadmium arachidate bilayers on graphite, we have observed bilayers of di-myristoyl-phosphatic acid (DMPA) on cleaved graphite, and studied monolayers of DMPA on oxidized graphite and on gold-coated calcite in air. We present the first images of a bilayer containing the protein concanavalin A. These experiments confirm the possibility of obtaining STM images by electron transport through layers of organic molecules more than 50 Å thick. Sample preparation, microscopic technique, and results are discussed.

Original language	English
Pages (from-to)	151-158
Number of pages	8
Journal	Chemical Physics Letters
Volume	145
Issue number	2
DOIs	https://doi.org/10.1016/0009-2614(88)80169-6
State	Published - Mar 1988

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title = "Scanning tunneling microscopy of lipid films and embedded biomolecules",

abstract = "We have observed the ordered molecular structure of fatty acid and phospholipid Langmuir-Blodgett films with a scanning tunneling microscope. Besides confirming earlier studies of cadmium arachidate bilayers on graphite, we have observed bilayers of di-myristoyl-phosphatic acid (DMPA) on cleaved graphite, and studied monolayers of DMPA on oxidized graphite and on gold-coated calcite in air. We present the first images of a bilayer containing the protein concanavalin A. These experiments confirm the possibility of obtaining STM images by electron transport through layers of organic molecules more than 50 {\AA} thick. Sample preparation, microscopic technique, and results are discussed.",

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year = "1988",

month = mar,

doi = "10.1016/0009-2614(88)80169-6",

language = "English",

volume = "145",

pages = "151--158",

journal = "Chemical Physics Letters",

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T1 - Scanning tunneling microscopy of lipid films and embedded biomolecules

AU - Hörber, J. K.H.

AU - Lang, C. A.

AU - Hänsch, T. W.

AU - Heckl, W. M.

AU - Möhwald, H.

PY - 1988/3

Y1 - 1988/3

N2 - We have observed the ordered molecular structure of fatty acid and phospholipid Langmuir-Blodgett films with a scanning tunneling microscope. Besides confirming earlier studies of cadmium arachidate bilayers on graphite, we have observed bilayers of di-myristoyl-phosphatic acid (DMPA) on cleaved graphite, and studied monolayers of DMPA on oxidized graphite and on gold-coated calcite in air. We present the first images of a bilayer containing the protein concanavalin A. These experiments confirm the possibility of obtaining STM images by electron transport through layers of organic molecules more than 50 Å thick. Sample preparation, microscopic technique, and results are discussed.

AB - We have observed the ordered molecular structure of fatty acid and phospholipid Langmuir-Blodgett films with a scanning tunneling microscope. Besides confirming earlier studies of cadmium arachidate bilayers on graphite, we have observed bilayers of di-myristoyl-phosphatic acid (DMPA) on cleaved graphite, and studied monolayers of DMPA on oxidized graphite and on gold-coated calcite in air. We present the first images of a bilayer containing the protein concanavalin A. These experiments confirm the possibility of obtaining STM images by electron transport through layers of organic molecules more than 50 Å thick. Sample preparation, microscopic technique, and results are discussed.

UR - https://www.scopus.com/pages/publications/0000678549

U2 - 10.1016/0009-2614(88)80169-6

DO - 10.1016/0009-2614(88)80169-6

M3 - Article

AN - SCOPUS:0000678549

SN - 0009-2614

VL - 145

SP - 151

EP - 158

JO - Chemical Physics Letters

JF - Chemical Physics Letters

IS - 2

ER -

Scanning tunneling microscopy of lipid films and embedded biomolecules

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