Ru(II) complexes with phosphine-functionalized NHC ligands in catalytic transfer hydrogenations

Johannes Mayr, Robert M. Reich, Fritz E. Kühn

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Catalytic transfer hydrogenations are essential chemical reactions for the production of a variety of fine chemicals. Ru(II) compounds are the most studied transition metals for this type of catalysis. This review deals in particular with Ru(II) based catalysts containing phosphane-functionalized NHC-ligands. Despite the otherwise widespread application of these multidentate systems as ligands in catalysis, Ru-catalyzed homogeneous transfer hydrogenations with such ligands have not yet been examined in great detail, in contrast to the predominant amine-functionalized NHC ligand systems. This review covers Ru(II) phosphane-functionalized NHC (pre)catalysts and their development, starting from complexes with monodentate imidazol-2-ylidene-NHC and abnormal imidazolylidene-NHC ligands to double substituted ruthenium complexes with two abnormally coordinating NHC ligands. The latter include the most active Ru-NHC complexes known in catalytic TH of the benchmark substrate acetophenone with TOF50% values up to 600,000 h−1.

Original languageEnglish
Title of host publicationAdvances in Organometallic Chemistry
EditorsPedro J. Pérez
PublisherAcademic Press Inc.
Pages135-156
Number of pages22
ISBN (Print)9780443188886
DOIs
StatePublished - Jan 2023

Publication series

NameAdvances in Organometallic Chemistry
Volume79
ISSN (Print)0065-3055

Keywords

  • Homogeneous catalysis
  • N-heterocyclic carbene
  • Ruthenium
  • Transfer hydrogenation

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