Role and function of liver sinusoidal endothelial cells

Percy A. Knolle

doi:10.1007/978-1-59745-518-3_3

Role and function of liver sinusoidal endothelial cells

Percy A. Knolle

University of Bonn and University Hospital Bonn

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

5 Scopus citations

Abstract

The liver holds a unique position with regard to the blood circulation. It receives venous blood draining from almost the entire gastrointestinal tract via the portal vein and from the systemic circulation via the hepatic artery. More than 2000 L of blood stream daily through the human liver, and peripheral blood leukocytes pass through the liver on average more than 300 times per day. These simple facts clearly demonstrate that the liver is a meeting point for antigens and leukocytes circulating in the blood.

Original language	English
Title of host publication	Liver Immunology
Subtitle of host publication	Principles and Practice
Publisher	Humana Press
Pages	25-39
Number of pages	15
ISBN (Print)	9781588298188
DOIs	https://doi.org/10.1007/978-1-59745-518-3_3
State	Published - 2007
Externally published	Yes

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10.1007/978-1-59745-518-3_3

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abstract = "The liver holds a unique position with regard to the blood circulation. It receives venous blood draining from almost the entire gastrointestinal tract via the portal vein and from the systemic circulation via the hepatic artery. More than 2000 L of blood stream daily through the human liver, and peripheral blood leukocytes pass through the liver on average more than 300 times per day. These simple facts clearly demonstrate that the liver is a meeting point for antigens and leukocytes circulating in the blood.",

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AB - The liver holds a unique position with regard to the blood circulation. It receives venous blood draining from almost the entire gastrointestinal tract via the portal vein and from the systemic circulation via the hepatic artery. More than 2000 L of blood stream daily through the human liver, and peripheral blood leukocytes pass through the liver on average more than 300 times per day. These simple facts clearly demonstrate that the liver is a meeting point for antigens and leukocytes circulating in the blood.

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PB - Humana Press

ER -

Role and function of liver sinusoidal endothelial cells

Abstract

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