@inproceedings{fe7385667fbe42dc9ee8c2155147ec07,
title = "Robust segmentation of brain structures in MRI",
abstract = "A novel method for the segmentation of brain structures combining registration-based and EM-based approaches is proposed. To address the issue of intensity variation within brain structures, we propose a method for creating spatial prior corresponding very well with the new subject anatomy, referred to as subject-specific atlas. The subject-specific atlas is created using multiple non-rigid registrations with the new subject, and therefore a robust non-rigid alignment of the prior with the image is achieved. The final EM segmentation step ensures a good quality classification of the complicated cortical structures based on intensity. The evaluation of the proposed method shows consistent results superior to both, registration-based and EM-based approaches.",
keywords = "Brain MRI, EM segmentation, Registration, Segmentation, Structures",
author = "Maria Murgasova and Daniel Rueckert and David Edwards and Jo Hajnal",
year = "2009",
doi = "10.1109/ISBI.2009.5192972",
language = "English",
isbn = "9781424439324",
series = "Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009",
pages = "17--20",
booktitle = "Proceedings - 2009 IEEE International Symposium on Biomedical Imaging",
note = "2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 ; Conference date: 28-06-2009 Through 01-07-2009",
}