Risikofaktoren und primäre Präventionsstrategien des Zervixkarzinoms: Inzidenz, Mortalität, Epidemiologie, HPV‑Impfung

T. Ganzenmüller; P. Soergel; S. Weinmann; S. J. Klug

doi:10.1007/s00761-020-00756-z

Risikofaktoren und primäre Präventionsstrategien des Zervixkarzinoms: Inzidenz, Mortalität, Epidemiologie, HPV‑Impfung

Translated title of the contribution: Risk factors and strategies for the primary prevention of cervical cancer: Incidence, mortality, epidemiology, and HPV vaccination

T. Ganzenmüller, P. Soergel, S. Weinmann, S. J. Klug

Chair of Epidemiology

Research output: Contribution to journal › Review article › peer-review

Abstract

Background: The main risk factor for the development of cervical cancer is persistent infection with human papillomavirus. The high-risk human papillomavirus (HPV) types 16 and 18 account for the majority of cases. Cervical cancer is the fourth most common cancer among women worldwide. In 2018, approximately 311,000 women died from invasive cervical cancer. Results: Since 2006, HPV vaccines are available as primary prevention strategies. In Germany, the Standing Committee on Vaccination (STIKO) recommends HPV vaccination for all girls and boys for the age from 9 to 14 years. In 2015, the coverage of complete HPV immunization among 15-year-old girls in Germany was only 31.2%. Worldwide, school-based vaccination programs are successful and reach high coverage. Conclusion: Therefore, the introduction of a school-based HPV vaccination program in Germany could help to increase vaccination rates and thus reduce HPV infections and the incidence of related cancers.

Translated title of the contribution	Risk factors and strategies for the primary prevention of cervical cancer: Incidence, mortality, epidemiology, and HPV vaccination
Original language	German
Pages (from-to)	583-590
Number of pages	8
Journal	Onkologe
Volume	26
Issue number	7
DOIs	https://doi.org/10.1007/s00761-020-00756-z
State	Published - 1 Jul 2020

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title = "Risikofaktoren und prim{\"a}re Pr{\"a}ventionsstrategien des Zervixkarzinoms: Inzidenz, Mortalit{\"a}t, Epidemiologie, HPV‑Impfung",

abstract = "Background: The main risk factor for the development of cervical cancer is persistent infection with human papillomavirus. The high-risk human papillomavirus (HPV) types 16 and 18 account for the majority of cases. Cervical cancer is the fourth most common cancer among women worldwide. In 2018, approximately 311,000 women died from invasive cervical cancer. Results: Since 2006, HPV vaccines are available as primary prevention strategies. In Germany, the Standing Committee on Vaccination (STIKO) recommends HPV vaccination for all girls and boys for the age from 9 to 14 years. In 2015, the coverage of complete HPV immunization among 15-year-old girls in Germany was only 31.2%. Worldwide, school-based vaccination programs are successful and reach high coverage. Conclusion: Therefore, the introduction of a school-based HPV vaccination program in Germany could help to increase vaccination rates and thus reduce HPV infections and the incidence of related cancers.",

keywords = "Cancer screening, HPV vaccination, Human papillomavirus (HPV), Prevalence, Uterine cervical neoplasms",

author = "T. Ganzenm{\"u}ller and P. Soergel and S. Weinmann and Klug, {S. J.}",

note = "Publisher Copyright: {\textcopyright} 2020, Springer Medizin Verlag GmbH, ein Teil von Springer Nature.",

year = "2020",

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doi = "10.1007/s00761-020-00756-z",

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T1 - Risikofaktoren und primäre Präventionsstrategien des Zervixkarzinoms

T2 - Inzidenz, Mortalität, Epidemiologie, HPV‑Impfung

AU - Ganzenmüller, T.

AU - Soergel, P.

AU - Weinmann, S.

AU - Klug, S. J.

PY - 2020/7/1

Y1 - 2020/7/1

N2 - Background: The main risk factor for the development of cervical cancer is persistent infection with human papillomavirus. The high-risk human papillomavirus (HPV) types 16 and 18 account for the majority of cases. Cervical cancer is the fourth most common cancer among women worldwide. In 2018, approximately 311,000 women died from invasive cervical cancer. Results: Since 2006, HPV vaccines are available as primary prevention strategies. In Germany, the Standing Committee on Vaccination (STIKO) recommends HPV vaccination for all girls and boys for the age from 9 to 14 years. In 2015, the coverage of complete HPV immunization among 15-year-old girls in Germany was only 31.2%. Worldwide, school-based vaccination programs are successful and reach high coverage. Conclusion: Therefore, the introduction of a school-based HPV vaccination program in Germany could help to increase vaccination rates and thus reduce HPV infections and the incidence of related cancers.

AB - Background: The main risk factor for the development of cervical cancer is persistent infection with human papillomavirus. The high-risk human papillomavirus (HPV) types 16 and 18 account for the majority of cases. Cervical cancer is the fourth most common cancer among women worldwide. In 2018, approximately 311,000 women died from invasive cervical cancer. Results: Since 2006, HPV vaccines are available as primary prevention strategies. In Germany, the Standing Committee on Vaccination (STIKO) recommends HPV vaccination for all girls and boys for the age from 9 to 14 years. In 2015, the coverage of complete HPV immunization among 15-year-old girls in Germany was only 31.2%. Worldwide, school-based vaccination programs are successful and reach high coverage. Conclusion: Therefore, the introduction of a school-based HPV vaccination program in Germany could help to increase vaccination rates and thus reduce HPV infections and the incidence of related cancers.

KW - Cancer screening

KW - HPV vaccination

KW - Human papillomavirus (HPV)

KW - Prevalence

KW - Uterine cervical neoplasms

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U2 - 10.1007/s00761-020-00756-z

DO - 10.1007/s00761-020-00756-z

M3 - Übersichtsartikel

AN - SCOPUS:85084133550

SN - 0947-8965

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IS - 7

ER -

Risikofaktoren und primäre Präventionsstrategien des Zervixkarzinoms: Inzidenz, Mortalität, Epidemiologie, HPV‑Impfung

Abstract

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