@article{26a6a81b8cb841b386ebb5124408b787,
title = "Rheumatoid arthritis association at 6q23",
abstract = "The Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs putatively associated with rheumatoid arthritis at P = 1 × 10 -5 - 5 × 10-7 in a genome-wide association screen. One, rs6920220, was unequivocally replicated (trend P = 1.1 × 10 -8) in a validation study, as described here. This SNP maps to 6q23, between the genes oligodendrocyte lineage transcription factor 3 (OLIG3) and tumor necrosis factor-α-induced protein 3 (TNFAIP3).",
author = "\{Wellcome Trust Case Control Consortium\} and \{YEAR Consortium\} and \{The Biologics in RA Genetics and Genomics BRAGGS\} and Wendy Thomson and Anne Barton and Xiayi Ke and Steve Eyre and Anne Hinks and John Bowes and Rachelle Donn and Symmons, \{Deborah P.\} and Samantha Hider and Bruce, \{Ian N.\} and Wilson, \{Anthony G.\} and Ioanna Marinou and Ann Morgan and Paul Emery and Angela Carter and Sophia Steer and Lynne Hocking and Reid, \{David M.\} and Paul Wordsworth and Pille Harrison and David Strachan and Jane Worthington and Burton, \{P. R.\} and Clayton, \{D. G.\} and Cardon, \{L. R.\} and N. Craddock and P. Deloukas and A. Duncanson and Kwiatkowski, \{D. P.\} and McCarthy, \{M. I.\} and Ouwehand, \{W. H.\} and Samani, \{N. J.\} and Todd, \{J. A.\} and P. Donnelly and Barrett, \{J. C.\} and D. Davison and D. Easton and D. Evans and Leung, \{H. T.\} and Marchini, \{J. L.\} and Morris, \{A. P.\} and Spencer, \{C. C.\} and Tobin, \{M. D.\} and Attwood, \{A. P.\} and Boorman, \{J. P.\} and B. Cant and U. Everson and Hussey, \{J. M.\} and Jolley, \{J. D.\} and E. Zeggini",
note = "Funding Information: Funding for this study was provided by the Arthritis Research Campaign (arc). We thank the Wellcome Trust for funding the WTCCC. We would also like to acknowledge the National Health Service (NHS) Research and Development Support Fund for Guy{\textquoteright}s and St Thomas{\textquoteright} and Lewisham NHS Trusts. We acknowledge use of DNA from the British 1958 Birth Cohort collection, funded by the Medical Research Council grant G0000934 and the Wellcome Trust grant 068545/Z/02. IT support was provided by M. Lay, and technical support was provided by P. Gilbert, B. Lad and S.G. Martin. Nursing support was provided by J. Grumley, J. Shotton and C. Farrar.",
year = "2007",
month = dec,
day = "1",
doi = "10.1038/ng.2007.32",
language = "English",
volume = "39",
pages = "1431--1433",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Research",
number = "12",
}