Reusable Co-nanoparticles for general and selectiveN-alkylation of amines and ammonia with alcohols

Zhuang Ma, Bei Zhou, Xinmin Li, Ravishankar G. Kadam, Manoj B. Gawande, Martin Petr, Radek Zbořil, Matthias Beller, Rajenahally V. Jagadeesh

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

A general cobalt-catalyzedN-alkylation of amines with alcohols by borrowing hydrogen methodology to prepare different kinds of amines is reported. The optimal catalyst for this transformation is prepared by pyrolysis of a specific templated material, which is generatedin situby mixing cobalt salts, nitrogen ligands and colloidal silica, and subsequent removal of silica. Applying this novel Co-nanoparticle-based material, >100 primary, secondary, and tertiary amines includingN-methylamines and selected drug molecules were conveniently prepared starting from inexpensive and easily accessible alcohols and amines or ammonia.

Original languageEnglish
Pages (from-to)111-117
Number of pages7
JournalChemical Science
Volume13
Issue number1
DOIs
StatePublished - 7 Jan 2022
Externally publishedYes

Fingerprint

Dive into the research topics of 'Reusable Co-nanoparticles for general and selectiveN-alkylation of amines and ammonia with alcohols'. Together they form a unique fingerprint.

Cite this