Regression and epithelial hyperplasia after myopic photorefractive keratectomy in a human cornea

Chris P. Lohmann, Udo Reischl, John Marshall

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

We present the histology of a cornea of a woman who had excimer laser photorefractive keratectomy (PRK) for myopia 6 months before she died in an accident. Preoperative spherical refraction was -6.00 diopters (D) with an astigmatism of -0.50 D. Six months postoperatively, refraction was -4.50 D. Slight corneal haze was noted at 1 and 3 months. The corneal histology show marked epithelial hyperplasia in the center of the ablation zone without subepithelial deposition of newly synthesized collagen, proteoglycans, or both. The epithelial thickness was 38 μm in the untreated area and 93 μm in the center of the ablation. In conclusion, postoperative epithelial hyperplasia was responsible for regression after PRK in this eye.

Original languageEnglish
Pages (from-to)712-715
Number of pages4
JournalJournal of Cataract and Refractive Surgery
Volume25
Issue number5
DOIs
StatePublished - May 1999
Externally publishedYes

Fingerprint

Dive into the research topics of 'Regression and epithelial hyperplasia after myopic photorefractive keratectomy in a human cornea'. Together they form a unique fingerprint.

Cite this