Registration of 3D fetal neurosonography and MRI

Maria Kuklisova-Murgasova, Amalia Cifor, Raffaele Napolitano, Aris Papageorghiou, Gerardine Quaghebeur, Mary A. Rutherford, Joseph V. Hajnal, J. Alison Noble, Julia A. Schnabel

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

We propose a method for registration of 3D fetal brain ultrasound with a reconstructed magnetic resonance fetal brain volume. This method, for the first time, allows the alignment of models of the fetal brain built from magnetic resonance images with 3D fetal brain ultrasound, opening possibilities to develop new, prior information based image analysis methods for 3D fetal neurosonography. The reconstructed magnetic resonance volume is first segmented using a probabilistic atlas and a pseudo ultrasound image volume is simulated from the segmentation. This pseudo ultrasound image is then affinely aligned with clinical ultrasound fetal brain volumes using a robust block-matching approach that can deal with intensity artefacts and missing features in the ultrasound images. A qualitative and quantitative evaluation demonstrates good performance of the method for our application, in comparison with other tested approaches. The intensity average of 27 ultrasound images co-aligned with the pseudo ultrasound template shows good correlation with anatomy of the fetal brain as seen in the reconstructed magnetic resonance image.

Original languageEnglish
Pages (from-to)1137-1150
Number of pages14
JournalMedical Image Analysis
Volume17
Issue number8
DOIs
StatePublished - Dec 2013
Externally publishedYes

Keywords

  • Block matching
  • Fetal 3D ultrasound
  • Fetal neurosonography
  • MR ultrasound registration

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