Reduction of lp(a) by different methods of plasma exchange

I. Schenck; Ch Keller; S. Hailer; G. Wolfram; N. Zöllner

doi:10.1007/BF01727423

Reduction of lp(a) by different methods of plasma exchange

I. Schenck, Ch Keller, S. Hailer, G. Wolfram, N. Zöllner

Ludwig-Maximilians-Universität München

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Lipoprotein(a) has been shown to be an independent risk factor for atherosclerosis. The effect of different forms of plasmapheresis therapy on the removal of Lp (a) is examined. Plasmapheresis is successfully administered in a small number of hypercholesteremic patients who fail to respond to conventional therapy. Comparison of four different methods of plasma exchange (albumin substitution, anti-apoB antibody column, LDL precipitation, filtration) reveals significant differences in effectiveness in the ability to lower plasma Lp(a): plasma exchange with albumin und LDL precipitation seem to be the most effective, plasma filtration the least.

Original language	English
Pages (from-to)	1197-1201
Number of pages	5
Journal	Klinische Wochenschrift
Volume	66
Issue number	24
DOIs	https://doi.org/10.1007/BF01727423
State	Published - Dec 1988
Externally published	Yes

Keywords

Familial hypercholesterolemia
LDL apheresis
Lp(a)

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10.1007/BF01727423

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abstract = "Lipoprotein(a) has been shown to be an independent risk factor for atherosclerosis. The effect of different forms of plasmapheresis therapy on the removal of Lp (a) is examined. Plasmapheresis is successfully administered in a small number of hypercholesteremic patients who fail to respond to conventional therapy. Comparison of four different methods of plasma exchange (albumin substitution, anti-apoB antibody column, LDL precipitation, filtration) reveals significant differences in effectiveness in the ability to lower plasma Lp(a): plasma exchange with albumin und LDL precipitation seem to be the most effective, plasma filtration the least.",

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author = "I. Schenck and Ch Keller and S. Hailer and G. Wolfram and N. Z{\"o}llner",

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AU - Schenck, I.

AU - Keller, Ch

AU - Hailer, S.

AU - Wolfram, G.

AU - Zöllner, N.

PY - 1988/12

Y1 - 1988/12

N2 - Lipoprotein(a) has been shown to be an independent risk factor for atherosclerosis. The effect of different forms of plasmapheresis therapy on the removal of Lp (a) is examined. Plasmapheresis is successfully administered in a small number of hypercholesteremic patients who fail to respond to conventional therapy. Comparison of four different methods of plasma exchange (albumin substitution, anti-apoB antibody column, LDL precipitation, filtration) reveals significant differences in effectiveness in the ability to lower plasma Lp(a): plasma exchange with albumin und LDL precipitation seem to be the most effective, plasma filtration the least.

AB - Lipoprotein(a) has been shown to be an independent risk factor for atherosclerosis. The effect of different forms of plasmapheresis therapy on the removal of Lp (a) is examined. Plasmapheresis is successfully administered in a small number of hypercholesteremic patients who fail to respond to conventional therapy. Comparison of four different methods of plasma exchange (albumin substitution, anti-apoB antibody column, LDL precipitation, filtration) reveals significant differences in effectiveness in the ability to lower plasma Lp(a): plasma exchange with albumin und LDL precipitation seem to be the most effective, plasma filtration the least.

KW - Familial hypercholesterolemia

KW - LDL apheresis

KW - Lp(a)

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EP - 1201

JO - Klinische Wochenschrift

JF - Klinische Wochenschrift

IS - 24

ER -

Reduction of lp(a) by different methods of plasma exchange

Abstract

Keywords

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