Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations

Carolina Wessel; Julia A. Schnabel; Michael Brady

doi:10.1109/EMBC.2013.6611231

Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations

Carolina Wessel
, Julia A. Schnabel
, Michael Brady

University of Oxford

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Scopus citations

Abstract

We develop a large deformations, Finite Elements biomechanical model of a stellate breast tumour, subject to prone to supine (MRI to US) breast deformations. Based on clinical findings, we introduce a volume of increased mammographic density/stiffness around a spiculated tumour, as well as a range of reported mechanical properties, both linear elastic and hyperelastic. This novel model demonstrates that these have a non-negligible effect on stresses and displacements, which, in turn, have implications, for example, in breast registration. We also show that the choice of material properties plays a dramatic effect on the mechanical variables.

Original language	English
Title of host publication	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages	7249-7252
Number of pages	4
DOIs	https://doi.org/10.1109/EMBC.2013.6611231
State	Published - 2013
Externally published	Yes
Event	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan Duration: 3 Jul 2013 → 7 Jul 2013

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Conference

Conference	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Country/Territory	Japan
City	Osaka
Period	3/07/13 → 7/07/13

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1109/EMBC.2013.6611231

Cite this

Wessel, C., Schnabel, J. A., & Brady, M. (2013). Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 7249-7252). Article 6611231 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6611231

Wessel, Carolina ; Schnabel, Julia A. ; Brady, Michael. / Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations. 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. pp. 7249-7252 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations",

abstract = "We develop a large deformations, Finite Elements biomechanical model of a stellate breast tumour, subject to prone to supine (MRI to US) breast deformations. Based on clinical findings, we introduce a volume of increased mammographic density/stiffness around a spiculated tumour, as well as a range of reported mechanical properties, both linear elastic and hyperelastic. This novel model demonstrates that these have a non-negligible effect on stresses and displacements, which, in turn, have implications, for example, in breast registration. We also show that the choice of material properties plays a dramatic effect on the mechanical variables.",

author = "Carolina Wessel and Schnabel, \{Julia A.\} and Michael Brady",

year = "2013",

doi = "10.1109/EMBC.2013.6611231",

language = "English",

isbn = "9781457702167",

series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",

pages = "7249--7252",

booktitle = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013",

note = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 ; Conference date: 03-07-2013 Through 07-07-2013",

}

Wessel, C, Schnabel, JA & Brady, M 2013, Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations. in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013., 6611231, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 7249-7252, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 3/07/13. https://doi.org/10.1109/EMBC.2013.6611231

Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations. / Wessel, Carolina; Schnabel, Julia A.; Brady, Michael.
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 7249-7252 6611231 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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N2 - We develop a large deformations, Finite Elements biomechanical model of a stellate breast tumour, subject to prone to supine (MRI to US) breast deformations. Based on clinical findings, we introduce a volume of increased mammographic density/stiffness around a spiculated tumour, as well as a range of reported mechanical properties, both linear elastic and hyperelastic. This novel model demonstrates that these have a non-negligible effect on stresses and displacements, which, in turn, have implications, for example, in breast registration. We also show that the choice of material properties plays a dramatic effect on the mechanical variables.

AB - We develop a large deformations, Finite Elements biomechanical model of a stellate breast tumour, subject to prone to supine (MRI to US) breast deformations. Based on clinical findings, we introduce a volume of increased mammographic density/stiffness around a spiculated tumour, as well as a range of reported mechanical properties, both linear elastic and hyperelastic. This novel model demonstrates that these have a non-negligible effect on stresses and displacements, which, in turn, have implications, for example, in breast registration. We also show that the choice of material properties plays a dramatic effect on the mechanical variables.

UR - https://www.scopus.com/pages/publications/84886552662

U2 - 10.1109/EMBC.2013.6611231

DO - 10.1109/EMBC.2013.6611231

M3 - Conference contribution

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AN - SCOPUS:84886552662

SN - 9781457702167

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ER -

Wessel C, Schnabel JA, Brady M. Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 7249-7252. 6611231. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2013.6611231

Realistic biomechanical model of a cancerous breast for the registration of prone to supine deformations

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