Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases

Thomas Wendler; Marco Feuerstein; Joerg Traub; Tobias Lasser; Jakob Vogel; Farhad Daghighian; Sibylle I. Ziegler; Nassir Navab

doi:10.1007/978-3-540-75759-7_31

Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases

Thomas Wendler
, Marco Feuerstein
, Joerg Traub
, Tobias Lasser
, Jakob Vogel
, Farhad Daghighian
, Sibylle I. Ziegler
, Nassir Navab

Informatics 16 - Chair of Computer Aided Medical Procedures

Technical University of Munich
IntraMedical Imaging LLC

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

21 Scopus citations

Abstract

Liver metastases are an advanced stage of several types of cancer, usually treated with surgery. Intra-operative localization of these lesions is currently facilitated by intra-operative ultrasound (IOUS) and palpation, yielding a high rate of false positives due to benign abnormal regions. In this paper we present the integration of functional nuclear information from a gamma probe with IOUS, to provide a synchronized, real-time visualization that facilitates the detection of active metastases intra-operatively. We evaluate the system in an ex-vivo setup employing a group of physicians and medical technicians and show that the addition of functional imaging improves the accuracy of localizing and identifying malignant and benign lesions significantly. Furthermore we are able to demonstrate that the inclusion of an advanced, augmented visualization provides more reliability and confidence on classifying these lesions in the presented evaluation setup.

Original language	English
Title of host publication	Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings
Publisher	Springer Verlag
Pages	252-260
Number of pages	9
Edition	PART 2
ISBN (Print)	9783540757580
DOIs	https://doi.org/10.1007/978-3-540-75759-7_31
State	Published - 2007
Event	10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007 - Brisbane, Australia Duration: 29 Oct 2007 → 2 Nov 2007

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Number	PART 2
Volume	4792 LNCS
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Conference

Conference	10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007
Country/Territory	Australia
City	Brisbane
Period	29/10/07 → 2/11/07

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1007/978-3-540-75759-7_31

Cite this

Wendler, T., Feuerstein, M., Traub, J., Lasser, T., Vogel, J., Daghighian, F., Ziegler, S. I., & Navab, N. (2007). Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases. In Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings (PART 2 ed., pp. 252-260). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4792 LNCS, No. PART 2). Springer Verlag. https://doi.org/10.1007/978-3-540-75759-7_31

Wendler, Thomas ; Feuerstein, Marco ; Traub, Joerg et al. / Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases. Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings. PART 2. ed. Springer Verlag, 2007. pp. 252-260 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2).

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title = "Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases",

abstract = "Liver metastases are an advanced stage of several types of cancer, usually treated with surgery. Intra-operative localization of these lesions is currently facilitated by intra-operative ultrasound (IOUS) and palpation, yielding a high rate of false positives due to benign abnormal regions. In this paper we present the integration of functional nuclear information from a gamma probe with IOUS, to provide a synchronized, real-time visualization that facilitates the detection of active metastases intra-operatively. We evaluate the system in an ex-vivo setup employing a group of physicians and medical technicians and show that the addition of functional imaging improves the accuracy of localizing and identifying malignant and benign lesions significantly. Furthermore we are able to demonstrate that the inclusion of an advanced, augmented visualization provides more reliability and confidence on classifying these lesions in the presented evaluation setup.",

author = "Thomas Wendler and Marco Feuerstein and Joerg Traub and Tobias Lasser and Jakob Vogel and Farhad Daghighian and Ziegler, \{Sibylle I.\} and Nassir Navab",

year = "2007",

doi = "10.1007/978-3-540-75759-7\_31",

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booktitle = "Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings",

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Wendler, T, Feuerstein, M, Traub, J, Lasser, T, Vogel, J, Daghighian, F, Ziegler, SI & Navab, N 2007, Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases. in Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings. PART 2 edn, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), no. PART 2, vol. 4792 LNCS, Springer Verlag, pp. 252-260, 10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007, Brisbane, Australia, 29/10/07. https://doi.org/10.1007/978-3-540-75759-7_31

Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases. / Wendler, Thomas; Feuerstein, Marco; Traub, Joerg et al.
Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings. PART 2. ed. Springer Verlag, 2007. p. 252-260 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4792 LNCS, No. PART 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

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AU - Wendler, Thomas

AU - Feuerstein, Marco

AU - Traub, Joerg

AU - Lasser, Tobias

AU - Vogel, Jakob

AU - Daghighian, Farhad

AU - Ziegler, Sibylle I.

AU - Navab, Nassir

PY - 2007

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N2 - Liver metastases are an advanced stage of several types of cancer, usually treated with surgery. Intra-operative localization of these lesions is currently facilitated by intra-operative ultrasound (IOUS) and palpation, yielding a high rate of false positives due to benign abnormal regions. In this paper we present the integration of functional nuclear information from a gamma probe with IOUS, to provide a synchronized, real-time visualization that facilitates the detection of active metastases intra-operatively. We evaluate the system in an ex-vivo setup employing a group of physicians and medical technicians and show that the addition of functional imaging improves the accuracy of localizing and identifying malignant and benign lesions significantly. Furthermore we are able to demonstrate that the inclusion of an advanced, augmented visualization provides more reliability and confidence on classifying these lesions in the presented evaluation setup.

AB - Liver metastases are an advanced stage of several types of cancer, usually treated with surgery. Intra-operative localization of these lesions is currently facilitated by intra-operative ultrasound (IOUS) and palpation, yielding a high rate of false positives due to benign abnormal regions. In this paper we present the integration of functional nuclear information from a gamma probe with IOUS, to provide a synchronized, real-time visualization that facilitates the detection of active metastases intra-operatively. We evaluate the system in an ex-vivo setup employing a group of physicians and medical technicians and show that the addition of functional imaging improves the accuracy of localizing and identifying malignant and benign lesions significantly. Furthermore we are able to demonstrate that the inclusion of an advanced, augmented visualization provides more reliability and confidence on classifying these lesions in the presented evaluation setup.

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SN - 9783540757580

T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

SP - 252

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BT - Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings

PB - Springer Verlag

T2 - 10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007

Y2 - 29 October 2007 through 2 November 2007

ER -

Wendler T, Feuerstein M, Traub J, Lasser T, Vogel J, Daghighian F et al. Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases. In Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings. PART 2 ed. Springer Verlag. 2007. p. 252-260. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2). doi: 10.1007/978-3-540-75759-7_31

Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases

Abstract

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