Rapid progression of a splenic aneurysm due to segmental arterial mediolysis: A rare cause of acute pancreatitis

J. Matthias Löhr, Dietmar Dinter, Steffen J. Diehl, Stephan L. Haas, Mira Veeser, Roland Pfützer, Jürgen Retter, Stefan O. Schönberg, Christoph Düber, Volker Keim, Dirk Schadendorf, Heiko Witt

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: The etiology of acute pancreatitis can be manifold, beside the usual causes.We are reporting an unusual cause that triggered acute pancreatitis. Patient & results: A 50 year-old male experienced attacks of acute pancreatitis (abdominal pain and elevated amylase and lipase) during sexual arousal. Serial imaging showed a rapidly-progressing, partlythrombosed splenic artery aneurysm, with local compression of the pancreas. After angiographic coiling, the attacks subsided. Further angiography revealed additional aneurysms consistent with segmental arterial mediolysis at other sites of the body. Molecular analysis regarding EhlerseDanlos-syndrome and genetic factors for pancreatitis, autoantibodies and Syphilis serology was negative. Conclusions: Acute pancreatitis was triggered by a transient rise in blood pressure during sexual stimulation, which caused rapid progression of a splenic artery aneurysm as part of systemic segmental arterial mediolysis.

Original languageEnglish
Pages (from-to)553-556
Number of pages4
JournalPancreatology
Volume13
Issue number5
DOIs
StatePublished - 2013

Keywords

  • Acute pancreatitis
  • Hypertension
  • Segmental arterial mediolysis
  • Sexual arousal
  • Splenic artery aneurysm

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