Radiation dose reduction in perfusion CT imaging of the brain using a 256-slice CT: 80 mAs versus 160 mAs

Isabelle Riederer, Claus Zimmer, Daniela Pfeiffer, Silke Wunderlich, Holger Poppert, Ernst J. Rummeny, Armin Huber

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Purpose: To examine CTP of the brain in real patient data after reducing tube current down to 80 mAs to decrease radiation dose. Methods: CTP was acquired in 60 suspected stroke patients with 80 (n: 30) or 160 (n: 30) mAs. Data were analyzed retrospectively by two independent readers. SNR, perfusion maps and image quality were compared in hypoperfused and non-affected areas. Results: SNR was significantly higher in CTP with 160 mAs compared to 80 mAs (p < 0.001) in non-affected regions, but there was no significant difference in hypoperfused regions. Overall, images with 80 mAs were rated worse than the ones with 160 mAs (3.0 ± 0.7 versus 4.0 ± 0.7), however, still as sufficient to detect proximal vessel occlusions. Conclusion: Tube current of 80 mAs is still sufficient for the detection of perfusion deficits of proximal vessel occlusions.

Original languageEnglish
Pages (from-to)188-193
Number of pages6
JournalClinical Imaging
Volume50
DOIs
StatePublished - 1 Jul 2018
Externally publishedYes

Keywords

  • CT perfusion
  • Low dose
  • Multi-slice CT
  • Radiation dose reduction
  • Stroke

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