Quantitative phase-contrast tomography of a liquid phantom using a conventional x-ray tube source

Julia Herzen, Tilman Donath, Franz Pfeiffer, Oliver Bunk, Celestino Padeste, Felix Beckmann, Andreas Schreyer, Christian David

Research output: Contribution to journalArticlepeer-review

100 Scopus citations

Abstract

Over the last few years, differential phase-contrast x-ray computed tomography (PC-CT) using a hard x-ray grating interferometer and polychromatic x-ray tube sources has been developed. The method allows for simultaneous determination of the attenuation coefficient and the refractive index decrement distribution inside an object in three dimensions. Here we report experimental results of our investigation on the quantitativeness and accuracy of this method. For this study, a phantom consisting of several tubes filled with chemically well-defined liquids was built and measured in PC-CT. We find, that the measured attenuation coefficients and refractive index decrements closely match calculated, theoretical values. Moreover, the study demonstrates, how substances with similar attenuation coefficient or refractive index decrement, can be uniquely distinguished by the simultaneous, quantitative measurement of both quantities.

Original languageEnglish
Pages (from-to)10010-10018
Number of pages9
JournalOptics Express
Volume17
Issue number12
DOIs
StatePublished - 8 Jun 2009

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