Quantitative multimodal x-ray tomography: Absorption-, phase- and darkfield-contrast

Martin Bech, Oliver Bunk, Tilman Donath, Robert Feidenhans'L, Christian David, Franz Pfeiffer

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


The basic principles of x-ray image formation in radiography have remained essentially unchanged since Röntgen first discovered x-rays over a hundred years ago. The conventional approach relies on x-ray absorption as the sole source of contrast and draws exclusively on ray or geometrical optics to describe and interpret image formation. This approach ignores another, potentially more useful source of contrast, namely phase and scattering information. Phase-contrast imaging techniques, which can be understood using wave optics rather than ray optics, offer ways to augment or complement standard absorption contrast by incorporating phase information. The recent development of grating based phase- and darkfield-contrast imaging with x-rays1 pawed the way for many potential applications to medical imaging and structure determination in material science. Here we present our recent contributions to the field of interferometric phase-contrast and dark-field x-ray imaging. We introduce a new material dependent scattering parameter, the Linear Diffusion Coefficient, and a quatititative mathematical formalism to extend the dark-field x-ray images into three dimensions by tomographic reconstruction. Further, the results of two experiments that illustrate the potential of dark-field imaging for computed tomography are shown.

Original languageEnglish
Title of host publicationMedical Imaging 2010
Subtitle of host publicationPhysics of Medical Imaging
EditionPART 1
StatePublished - 2010
EventMedical Imaging 2010: Physics of Medical Imaging - San Diego, CA, United States
Duration: 15 Feb 201018 Feb 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
NumberPART 1
ISSN (Print)1605-7422


ConferenceMedical Imaging 2010: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego, CA


  • Biomedical imaging
  • Computed tomography
  • Dark-field
  • Grating interferometer
  • Phase-contrast


Dive into the research topics of 'Quantitative multimodal x-ray tomography: Absorption-, phase- and darkfield-contrast'. Together they form a unique fingerprint.

Cite this