Proteomics in Pathology

Rémi Longuespée; Rita Casadonte; Kristina Schwamborn; David Reuss; Daniel Kazdal; Katharina Kriegsmann; Andreas von Deimling; Wilko Weichert; Peter Schirmacher; Jörg Kriegsmann; Mark Kriegsmann

doi:10.1002/pmic.201700361

Proteomics in Pathology

Rémi Longuespée
, Rita Casadonte
, Kristina Schwamborn
, David Reuss
, Daniel Kazdal
, Katharina Kriegsmann
, Andreas von Deimling
, Wilko Weichert
, Peter Schirmacher
, Jörg Kriegsmann
, Mark Kriegsmann

Chair of Pathology

Universitätsklinikum Heidelberg
Proteopath GmbH
Technical University of Munich
German Cancer Research Center
Cytology and Molecular Diagnostics

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Proteomic approaches are of growing importance in the biologist's toolbox. It greatly benefited from past and recent advances in sampling, chemical processing, mass spectrometry (MS) instrumentation, and data processing. MS-based analysis of proteins is now in the process of being translated in pathology for objective diagnoses. In this viewpoint, we present the workflows that we think are the most promising for applications in pathology. We also comment what we think are prerequisites for a successful translational implementation.

Original language	English
Article number	1700361
Journal	Proteomics
Volume	18
Issue number	2
DOIs	https://doi.org/10.1002/pmic.201700361
State	Published - Jan 2018

Keywords

Biomarker discovery
Diagnostics
Molecular pathology
Tissue typing
Transnational proteomics

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10.1002/pmic.201700361

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title = "Proteomics in Pathology",

abstract = "Proteomic approaches are of growing importance in the biologist's toolbox. It greatly benefited from past and recent advances in sampling, chemical processing, mass spectrometry (MS) instrumentation, and data processing. MS-based analysis of proteins is now in the process of being translated in pathology for objective diagnoses. In this viewpoint, we present the workflows that we think are the most promising for applications in pathology. We also comment what we think are prerequisites for a successful translational implementation.",

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AU - Longuespée, Rémi

AU - Casadonte, Rita

AU - Schwamborn, Kristina

AU - Reuss, David

AU - Kazdal, Daniel

AU - Kriegsmann, Katharina

AU - von Deimling, Andreas

AU - Weichert, Wilko

AU - Schirmacher, Peter

AU - Kriegsmann, Jörg

AU - Kriegsmann, Mark

PY - 2018/1

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AB - Proteomic approaches are of growing importance in the biologist's toolbox. It greatly benefited from past and recent advances in sampling, chemical processing, mass spectrometry (MS) instrumentation, and data processing. MS-based analysis of proteins is now in the process of being translated in pathology for objective diagnoses. In this viewpoint, we present the workflows that we think are the most promising for applications in pathology. We also comment what we think are prerequisites for a successful translational implementation.

KW - Biomarker discovery

KW - Diagnostics

KW - Molecular pathology

KW - Tissue typing

KW - Transnational proteomics

UR - https://www.scopus.com/pages/publications/85040864188

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SN - 1615-9853

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JO - Proteomics

JF - Proteomics

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M1 - 1700361

ER -

Proteomics in Pathology

Abstract

Keywords

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