Abstract
Structural dynamics is essential for the biological function of proteins. Results from new experimental techniques should be compared with those from previous experiments in order to obtain a consistent picture of the physics of intramolecular fluctuations and conformational changes. The high intensity and time structure of synchrotron radiation have made possible time-resolved X-ray structure analysis and the determination of phonon density spectra through the Mössbauer effect. By combining results from Mössbauer absorption spectroscopy, incoherent neutron scattering, low-temperature crystallography and optical spectroscopy, a physical picture of protein dynamics emerges.
| Original language | English |
|---|---|
| Pages (from-to) | 552-557 |
| Number of pages | 6 |
| Journal | Current Opinion in Structural Biology |
| Volume | 13 |
| Issue number | 5 |
| DOIs | |
| State | Published - 1 Oct 2003 |