Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions

Mariangela Agamennone, Alessandro Nicoli, Sebastian Bayer, Verena Weber, Luca Borro, Shailendra Gupta, Marialuigia Fantacuzzi, Antonella Di Pizio

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

Protein-protein interactions (PPIs) play a key role in many biological processes and are intriguing targets for drug discovery campaigns. Advancements in experimental and computational techniques are leading to a growth of data accessibility, and, with it, an increased need for the analysis of PPIs. In this respect, visualization tools are essential instruments to represent and analyze biomolecular interactions. In this chapter, we reviewed some of the available tools, highlighting their features, and describing their functions with practical information on their usage.

Original languageEnglish
Title of host publicationBiomolecular Interactions Part A
EditorsArun K. Shukla
PublisherAcademic Press Inc.
Pages271-307
Number of pages37
ISBN (Print)9780128233511
DOIs
StatePublished - Jan 2021
Externally publishedYes

Publication series

NameMethods in Cell Biology
Volume166
ISSN (Print)0091-679X

Keywords

  • 3D representation
  • Molecular interactions
  • Protein
  • Protein interface
  • Protein photorealism
  • Protein-protein interactions
  • Surface

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