Protein crystallizability.

Pawel Smialowski, Dmitrij Frishman

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Obtaining well-diffracting crystals remains a major challenge in protein structure research. In this chapter, we review currently available computational methods to estimate the crystallization potential of a protein, to optimize amino acid sequences toward improved crystallization likelihood, and to design optimal crystal screen conditions.

Original languageEnglish
Pages (from-to)385-400
Number of pages16
JournalMethods in molecular biology (Clifton, N.J.)
StatePublished - 2010
Externally publishedYes


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