Protective lifelines: Tunneling nanotubes connect neurons and microglia

Jonas J. Neher; Mikael Simons

doi:10.1016/j.neuron.2024.07.027

Protective lifelines: Tunneling nanotubes connect neurons and microglia

Research output: Contribution to journal › Article › peer-review

Abstract

Tunneling nanotubes (TNTs) facilitate the exchange of intracellular cargo between cells. In this issue of Neuron, Scheiblich et al.1 reveal that TNTs selectively mediate the bidirectional transfer of cytoplasmic protein aggregates from neurons to microglia and mitochondria from microglia to neurons, thereby preserving neuronal health.

Original language	English
Pages (from-to)	2991-2993
Number of pages	3
Journal	Neuron
Volume	112
Issue number	18
DOIs	https://doi.org/10.1016/j.neuron.2024.07.027
State	Published - 25 Sep 2024
Externally published	Yes

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10.1016/j.neuron.2024.07.027

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title = "Protective lifelines: Tunneling nanotubes connect neurons and microglia",

abstract = "Tunneling nanotubes (TNTs) facilitate the exchange of intracellular cargo between cells. In this issue of Neuron, Scheiblich et al.1 reveal that TNTs selectively mediate the bidirectional transfer of cytoplasmic protein aggregates from neurons to microglia and mitochondria from microglia to neurons, thereby preserving neuronal health.",

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Protective lifelines: Tunneling nanotubes connect neurons and microglia

Abstract

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