Prostate-specific membrane antigen – Guided surgery

Tobias Maurer, Markus Graefen, Henk van der Poel, Freddie Hamdy, Alberto Briganti, Matthias Eiber, Hans Jürgen Wester, Fijs W.B. van Leeuwen

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)–ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.

Original languageEnglish
Pages (from-to)6-12
Number of pages7
JournalJournal of Nuclear Medicine
Volume61
Issue number1
DOIs
StatePublished - Jan 2020

Keywords

  • Fluorescence
  • Image-guided surgery
  • Lymph node dissection
  • Prostate cancer
  • Salvage

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