Prolonged norovirus infections correlate to quasispecies evolution resulting in structural changes of surface-exposed epitopes

Keyphrases

• Structural Change 100%
• Genome Complexity 100%
• Molecular Dynamics Simulation 100%
• Epitope 100%
• Quasispecies Evolution 100%
• Genetic Distance 100%
• Chronic Infection 100%
• Norovirus Infection 100%
• Protein Structure 50%
• Amino Acids 50%
• Surface Changes 50%
• Immune Escape 50%
• Infected Patients 50%
• Deep Sequencing 50%
• Sequential Samples 50%
• Capsid Gene 50%
• Ligand Binding 50%
• Capsid Sequence 50%
• Capsid Protein 50%
• Protein Surface 50%
• Antigenic Epitope 50%
• Stool Samples 50%
• Specific Antibodies 50%
• Norovirus 50%
• Norovirus Replication 50%
• P2 Domain 50%
• Capsid 50%
• Amino Acid Substitution 50%
• Quasispecies 50%

Immunology and Microbiology

• Epitope 100%
• Capsid 100%
• Quasispecies 100%
• Norovirus 100%
• Computer Simulation 50%
• Immune Escape 25%
• Protein Structure 25%
• Amino Acid Substitution 25%
• Antibodies 25%
• Amino Acid 25%
• Ligand Binding 25%